INT156084
From wiki-pain
(Difference between revisions)
Latest revision as of 18:12, 20 September 2012
| Context
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Info
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| Confidence
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0.02
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| First Reported
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2009
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| Last Reported
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2009
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| Negated
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1
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| Speculated
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0
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| Reported most in
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Abstract
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| Documents
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1
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| Total Number
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1
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| Disease Relevance
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0.31
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| Pain Relevance
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0.30
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[edit] Sentences Mentioned In
| Key:
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Protein
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Mutation
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Event
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Anatomy
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Negation
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Speculation
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Pain term
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Disease term
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| Using known structure-activity relationships for the inhibition of PGHS-1 and PGHS-2 by indole acetic acids we obtained N-(4-chlorobenzoyl)-melatonin as a specific AKR1C3 inhibitor (K(I)=6.0muM) that does not inhibit PGHS-1, PGHS-2, AKR1C1, or AKR1C2.
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