INT157022

Context Info Confidence 0.41 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.34 Pain Relevance 0.17

cytosol (EIF2S1) RNA binding (EIF2S1) nucleus (EIF2S1) translation (EIF2S1) cytoplasm (EIF2S1)

EIF2S1 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 1 84.84 Inflammation 1 84.36 ischemia 1 80.36

Disease Link Frequency Relevance Heat Stress 11 99.82 Apoptosis 1 98.36 INFLAMMATION 1 84.36 Cv General 4 Under Development 1 80.36 Disease 4 79.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

ER stress-induced phosphorylation of alpha-subunit of eukaryotic initiation factor-2 (eIF2alpha) has been reported to be involved in CHOP induction.

Negative_regulation (involved) of Phosphorylation (phosphorylation) of eIF2alpha associated with stress

1) Confidence 0.41 Published 2009 Journal Neurochem. Int. Section Abstract Doc Link 19114067 Disease Relevance 1.34 Pain Relevance 0.17

General Comments

This test has worked.