INT157670

Context Info Confidence 0.44 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.58 Pain Relevance 0

cytosol (PSMC6) nucleoplasm (PSMC6) small molecule metabolic process (PSMC6) ATPase activity (PSMC6) nucleus (PSMC6) protein binding, bridging (PSMC6)

Anatomy Link Frequency coronary artery 1 PSMC6 (Homo sapiens)

Pain Link Frequency Relevance Heat opiate 1 33.84 narcan 2 31.92 opioid receptor 1 25.00

Disease Link Frequency Relevance Heat Cv Unclassified Under Development 7 90.24 Infarction 1 80.08 Necrosis 1 53.84 Reperfusion Injury 1 25.00 Coronary Artery Disease 1 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Using a Langendorff preparation, we show that infarct size after coronary artery ligation and reperfusion was substantially reduced by rIPC in vivo, this stimulus up-regulating the MAPKs (mitogen-activating protein kinases) p42/p44, and inducing PKCepsilon (protein kinase Cepsilon) subcellular redistribution.

Regulation (regulating) of p44 in coronary artery

1) Confidence 0.44 Published 2009 Journal Clin. Sci. Section Abstract Doc Link 19175358 Disease Relevance 0.58 Pain Relevance 0

General Comments

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