INT157812

Context Info Confidence 0.11 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0

cytoplasm (TGFB1, Pmfbp1) aging (TGFB1) enzyme binding (TGFB1) embryo development (TGFB1) extracellular space (TGFB1) extracellular region (TGFB1)

Anatomy Link Frequency stellate cell 1 TGFB1 (Homo sapiens) Pmfbp1 (Mus musculus)

Pain Link Frequency Relevance Heat fibrosis 3 50.00 Chronic pancreatitis 1 5.00 Inflammation 1 5.00

Disease Link Frequency Relevance Heat Fibrosis 3 64.68 Pancreatitis 1 5.00 INFLAMMATION 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In culture, halofuginone inhibited pancreatic stellate cell (PSC) proliferation and TGFbeta-dependent increase in Cygb/STAP and transgelin synthesis and metalloproteinase 2 activity.

TGFbeta Positive_regulation (increase) of STAP in stellate cell

1) Confidence 0.11 Published 2009 Journal Pancreas Section Body Doc Link 19188864 Disease Relevance 0.06 Pain Relevance 0

General Comments

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