INT157846

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 27
Disease Relevance 15.89
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (BCS1L) mitochondrion organization (BCS1L)
Anatomy Link Frequency
lymph nodes 1
NB3 1
finger 1
tooth 1
BCS1L (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 442 100.00 Very High Very High Very High
Spinal cord 15 54.56 Quite High
Bioavailability 7 34.60 Quite Low
cva 1 31.00 Quite Low
cocaine 1 7.44 Low Low
Central nervous system 27 5.00 Very Low Very Low Very Low
Neuropathic pain 18 5.00 Very Low Very Low Very Low
alcohol 16 5.00 Very Low Very Low Very Low
depression 16 5.00 Very Low Very Low Very Low
member 8 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 462 100.00 Very High Very High Very High
INFLAMMATION 445 100.00 Very High Very High Very High
Premature Birth 135 100.00 Very High Very High Very High
Cancer 1285 98.80 Very High Very High Very High
Infection 11 95.56 Very High Very High Very High
Night Blindness 88 94.24 High High
Solid Tumor 15 94.08 High High
Bacterial Vaginosis 3 93.84 High High
Adenocarcinoma 15 90.48 High High
Recurrence 48 90.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For PTD, the potential exposure window was expressed in trimesters.


Gene_expression (expressed) of PTD associated with premature birth
1) Confidence 0.50 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1480490 Disease Relevance 0.27 Pain Relevance 0
The results of these trials revealed no differences in PTD rates with the use of antibiotics.17,18
Gene_expression (rates) of PTD associated with premature birth
2) Confidence 0.48 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697509 Disease Relevance 1.83 Pain Relevance 0
Univariate and multivariate analysis of uPA and PAI-1 mRNA values for BCS
Gene_expression (analysis) of BCS
3) Confidence 0.27 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1564186 Disease Relevance 0.98 Pain Relevance 0
In contrast, uPA expression levels were not significantly different between breast cancers (data not shown; Mann-Whitney p = 0.09 and p = 0.11 for MFS and BCS, respectively).


Gene_expression (expression) of BCS associated with breast cancer
4) Confidence 0.24 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1564186 Disease Relevance 0.59 Pain Relevance 0
In a Cox-multivariate regression analysis, only tumor size (p = 0.05), age categories (p = 0.04), and PAI-1 mRNA expression (p = 0.0003) are of prognostic value for BCS while number of lymph nodes, histological type, histological grade and uPA expression did not add any significant independent prognostic value (Table 4).


Gene_expression (expression) of BCS in lymph nodes associated with cancer
5) Confidence 0.24 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1564186 Disease Relevance 0.84 Pain Relevance 0
Expansion of BCS biowaivers to some class II and class III drugs (14)Development of biorelevant dissolution (15,16,17)Mechanistic understanding of food effectsBioequivalence methods for highly variable drugs (18)

Bioequivalence Methods for Locally Acting Drugs

Gene_expression (Expansion) of BCS
6) Confidence 0.23 Published 2008 Journal AAPS J Section Body Doc Link PMC2751455 Disease Relevance 0 Pain Relevance 0
CASE REPORT: A male patient, 25-year-old, facing tooth postextraction complications, was presented with acute BCS.
Gene_expression (presented) of BCS in tooth
7) Confidence 0.23 Published 2009 Journal Vojnosanit Pregl Section Body Doc Link 19195269 Disease Relevance 0 Pain Relevance 0
Immunohistochemistry to observe the subcellular localization of TRPM1–3×Flag expressed in the electroporated ON BCs was performed on sections as previously described [23].
Gene_expression (expressed) of BCs
8) Confidence 0.08 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2838739 Disease Relevance 0 Pain Relevance 0
These results in human and mice strongly indicated that TRPM1 is essential for the function of ON BCs in the visual pathway.
Gene_expression (essential) of BCs
9) Confidence 0.08 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2838739 Disease Relevance 0.55 Pain Relevance 0
Gene expression data of 51 of the 54 BCs and 4 normal breast (NB) samples (NB1, NB2, NB3 and NB4, representing samples from 4 women and 3 commercial pools of respectively 1, 2 and 4 normal breast RNA, Clontech, Palo Alto, CA) were quantified by using whole-genome DNA microarrays (HG-U133 plus 2.0, Affymetrix).
Gene_expression (expression) of BCs in NB3
10) Confidence 0.07 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.06 Pain Relevance 0
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (include) of BCs associated with inflammation
11) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.90 Pain Relevance 0.10
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (non) of BCs associated with inflammation
12) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.90 Pain Relevance 0.10
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (include) of BCs associated with inflammation
13) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.91 Pain Relevance 0.10
Markers and targets in ERBB2-amplified BCs
Gene_expression (amplified) of BCs
14) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.81 Pain Relevance 0.11
TRPS1 encodes a zinc finger transcription factor widely expressed in human tissues and overexpressed in BCs [65].
Gene_expression (overexpressed) of BCs in finger
15) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.75 Pain Relevance 0
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (non) of BCs associated with inflammation
16) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.96 Pain Relevance 0.10
35 years) and older women BCs (OWBCs, ?
Gene_expression (years) of BCs
17) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.95 Pain Relevance 0.10
IGF1R status was assessed in 30 ERBB2-amplified BCs for which ERBB2 IHC status had been determined (Figure 5).
Gene_expression (assessed) of BCs
18) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.35 Pain Relevance 0
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (include) of BCs associated with inflammation
19) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.97 Pain Relevance 0.10
These include inflammatory BCs (IBCs), non-inflammatory BCs (NIBC), very young women BCs (YWBCs, ?
Gene_expression (non) of BCs associated with inflammation
20) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.90 Pain Relevance 0.10

General Comments

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