INT157904

Context Info Confidence 0.39 First Reported 2009 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 1.35 Pain Relevance 3.01

CSE (Homo sapiens)

Pain Link Frequency Relevance Heat epidural 308 100.00 analgesia 234 98.08 backache 2 94.16 Opioid 54 94.08 anesthesia 16 92.72 depression 16 91.24 Dismenorea 4 85.04 headache 20 79.60 Pain 56 74.48 Catecholamine 4 73.36

Disease Link Frequency Relevance Heat Low Back Pain 2 94.16 Respiratory Failure 14 91.24 Cv Unclassified Under Development 40 88.52 Muscle Hypertonia 2 87.64 Dysmenorrhea 4 85.04 Post-dural Puncture Headache 16 81.20 Pain 55 74.48 Headache 4 39.36 Vomiting 14 17.40 Pruritus 22 16.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Concerns of CSE for labor

Positive_regulation (Concerns) of Gene_expression (Concerns) of CSE associated with epidural

1) Confidence 0.39 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 0.73 Pain Relevance 1.72

Comparison of CSE with conventional epidural technique for labor analgesia

Positive_regulation (Comparison) of Gene_expression (Comparison) of CSE associated with epidural and analgesia

2) Confidence 0.39 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 0.56 Pain Relevance 1.29

Either the activity or protein expression of pancreatic CSE increased after the development of caerulein-induced pancreatitis in mice.

Positive_regulation (increased) of Gene_expression (expression) of CSE

3) Confidence 0.10 Published 2009 Journal Gut Section Body Doc Link 19201768 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.