INT158175

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Context Info
Confidence 0.48
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RYR1) transmembrane transport (RYR1) cytoplasm (RYR1)
Anatomy Link Frequency
muscle 2
CCO 2
RYR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 120 99.32 Very High Very High Very High
anesthesia 1 25.00 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Channelopathies 5 99.12 Very High Very High Very High
Muscle Disease 51 97.92 Very High Very High Very High
Arrhythmia Under Development 2 92.80 High High
Cv General 2 Under Development 1 90.76 High High
Heart Rate Under Development 2 89.16 High High
Hypopituitarism 3 68.80 Quite High
Pressure And Volume Under Development 5 51.36 Quite High
Nemaline Myopathy 1 34.12 Quite Low
Disease 23 24.40 Low Low
Congenital Structural Myopathies 2 12.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Typical muscle imaging findings of patients with proven mutations in the DNM2, SEPN1, ACTA1, RYR1 and collagen 6A1 are provided

Muscle channelopathies and metabolic myopathies

Positive_regulation (mutations) of Gene_expression (6A1) of RYR1 in muscle associated with muscle disease, channelopathies and imagery
1) Confidence 0.48 Published 2010 Journal Eur Radiol Section Body Doc Link PMC2940021 Disease Relevance 1.00 Pain Relevance 0.13
When the CCO was switched off, no more arrhythmias were observed.
Positive_regulation (When) of Gene_expression (switched) of CCO in CCO
2) Confidence 0.42 Published 2009 Journal Lab. Anim. Section Abstract Doc Link 19237458 Disease Relevance 0.36 Pain Relevance 0

General Comments

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