INT158809

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.28
Pain Relevance 2.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pag1) intracellular (Pag1)
Anatomy Link Frequency
neurons 1
Pag1 (Mus musculus)
Rvm (Mus musculus)
Pain Link Frequency Relevance Heat
Rostral ventromedial medulla 3 100.00 Very High Very High Very High
Morphine 4 99.58 Very High Very High Very High
tolerance 9 98.76 Very High Very High Very High
Antinociceptive 1 94.00 High High
tail-flick 3 91.12 High High
Opioid 7 86.48 High High
antagonist 1 85.92 High High
Pain 6 82.84 Quite High
Analgesic 4 75.00 Quite High
antinociception 1 74.00 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 11 100.00 Very High Very High Very High
Nociception 3 99.52 Very High Very High Very High
Pain 3 82.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In metamizol-tolerant rats morphine microinjection into PAG also failed to affect RVM neurons or nociception (cross-tolerance).
PAG Neg (failed) Regulation (affect) of RVM in neurons associated with nociception, tolerance, urological neuroanatomy, rostral ventromedial medulla and morphine
1) Confidence 0.02 Published 2009 Journal Eur. J. Neurosci. Section Abstract Doc Link 19302154 Disease Relevance 1.28 Pain Relevance 2.33

General Comments

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