INT159351

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nos1, Nos2) cytosol (Nos1, Nos2) oxidoreductase activity (Nos1, Nos2)
nucleus (Nos1, Nos2) mitochondrion (Nos1) peroxisome (Nos2)
Nos1 (Mus musculus)
Nos2 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 1 97.20 Very High Very High Very High
Pain 2 96.00 Very High Very High Very High
Tetrahydrobiopterin 1 79.20 Quite High
Potency 1 74.48 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 97.80 Very High Very High Very High
Pain 1 96.00 Very High Very High Very High
Endotoxemia 1 95.36 Very High Very High Very High
Disease 1 50.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
KLYP956 thus represents the first nonimidazole-based inhibitor of iNOS and nNOS dimerization and provides a novel pharmaceutical alternative to previously described substrate competitive inhibitors.
Negative_regulation (inhibitor) of nNOS Binding (dimerization) of iNOS
1) Confidence 0.27 Published 2009 Journal Mol. Pharmacol. Section Abstract Doc Link 19364813 Disease Relevance 0.34 Pain Relevance 0.22

General Comments

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