INT160801

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Context Info
Confidence 0.59
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.99
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (OTC) small molecule metabolic process (OTC) cellular nitrogen compound metabolic process (OTC)
cytoplasm (OTC)
OTC (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 98.08 Very High Very High Very High
Paracetamol 3 94.84 High High
Analgesic 3 89.04 High High
tolerance 7 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 97.84 Very High Very High Very High
Hemorrhage 1 96.16 Very High Very High Very High
Diarrhoea 1 96.00 Very High Very High Very High
Injury 6 93.84 High High
Syndrome 3 92.04 High High
Exanthema 2 78.72 Quite High
Cognitive Disorder 1 77.28 Quite High
Disease 82 62.84 Quite High
Bacillus Anthracis Infection 3 52.24 Quite High
Lifespan 1 35.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The new labeling is required for all OTC IAAA drug products whether marketed under an OTC drug monograph or an approved new drug application (NDA).
Gene_expression (products) of OTC
1) Confidence 0.59 Published 2009 Journal Fed Regist Section Abstract Doc Link 19507324 Disease Relevance 0.29 Pain Relevance 0.36
For the same reasons height increasing pills are widely available in India as OTC products and are widely advertised through advertisements in newspapers and TV channels.
Gene_expression (products) of OTC
2) Confidence 0.57 Published 2010 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC3013560 Disease Relevance 0.08 Pain Relevance 0
NAC and OTC were applied with SM simultaneously and acetaminophen 30 min before SM exposure, incubated for 1 h and then were rinsed and incubated with fresh medium.
Gene_expression (applied) of OTC
3) Confidence 0.47 Published 2009 Journal Iran. Biomed. J. Section Body Doc Link 19946347 Disease Relevance 0 Pain Relevance 0
It also groups sales data of OTC products into analytic product categories relevant to public health surveillance (e.g., bronchial remedies, diarrhoea remedies, etc.) [55,56].
Gene_expression (products) of OTC associated with diarrhoea
4) Confidence 0.21 Published 2004 Journal Int J Health Geogr Section Body Doc Link PMC343292 Disease Relevance 0.62 Pain Relevance 0
Seen in this light, their description of the carbamoyltransferase dataset is useful, but I think it might help if the authors were to address the relevance of this single example of paralogous gene loss more explicitly and in more detail; i.e. how much more of the data do they think can be explained unambiguously as losses?
Gene_expression (dataset) of carbamoyltransferase
5) Confidence 0.07 Published 2008 Journal Biol Direct Section Body Doc Link PMC2478661 Disease Relevance 0 Pain Relevance 0
Moreover, a tree made with nearly 3,000 homologous carbamoyltransferases corresponding to at least five different enzymatic activities (our very recent unpublished results) confirms that the primary duplications that produced differentiated genes from an ancestral, substrate ambiguous carbamoyltransferase was already an ancient event in the evolution of LUCA.
Gene_expression (produced) of carbamoyltransferase
6) Confidence 0.06 Published 2008 Journal Biol Direct Section Body Doc Link PMC2478661 Disease Relevance 0 Pain Relevance 0

General Comments

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