INT1619

Context Info Confidence 0.14 First Reported 1979 Last Reported 1979 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 1.13

mitochondrion (Gad1) lyase activity (Gad1) plasma membrane (Oprl1) intracellular (Gad1) signal transducer activity (Oprl1) cytoplasm (Gad1)

Anatomy Link Frequency dorsal 1 Gad1 (Rattus norvegicus) Oprl1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Dorsal horn 4 100.00 dorsal rhizotomy 3 100.00 opiate 2 100.00 substance P 9 97.76 Peripheral nerve injury 1 95.52 Sciatic nerve 3 86.16 Neurotransmitter 1 85.92 Spinal cord 2 75.00

Disease Link Frequency Relevance Heat Nervous System Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Glutamic acid decarboxylase activity in the dorsal horn was unaffected by dorsal rhizotomy whereas opiate receptor binding was reduced by 40%.

Glutamic acid decarboxylase Binding (binding) of opiate receptor in dorsal associated with dorsal rhizotomy, dorsal horn and opiate

1) Confidence 0.14 Published 1979 Journal Brain Res. Section Abstract Doc Link 221070 Disease Relevance 0 Pain Relevance 1.13

General Comments

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