INT162046

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (OSM) extracellular space (OSM) extracellular region (OSM)
Anatomy Link Frequency
MDMs 1
kidney 1
OSM (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 91.08 High High
Inflammation 11 83.88 Quite High
Angina 1 81.16 Quite High
Inflammatory response 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 8 93.24 High High
Leukemia 1 85.16 High High
INFLAMMATION 12 83.88 Quite High
Myocardial Infarction 2 83.12 Quite High
Cv General 3 Under Development 1 81.16 Quite High
Stroke 1 80.48 Quite High
Disease 9 74.80 Quite High
Adhesions 2 38.80 Quite Low
Stress Incontinence 4 33.40 Quite Low
Atherosclerosis 9 9.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In MDMs, the effect of thrombin on OSM was abolished by PPACK and mimicked by a PAR-1-specific peptide.
Negative_regulation (effect) of OSM in MDMs
1) Confidence 0.41 Published 2009 Journal Blood Section Abstract Doc Link 19652200 Disease Relevance 1.04 Pain Relevance 0.31
Inactivation of IL6ST, a component of the functional receptors for LIF and OSM, leads to developmental defects in the kidney [53,54].
Negative_regulation (Inactivation) of OSM in kidney
2) Confidence 0.24 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.09 Pain Relevance 0

General Comments

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