INT163440

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.65
Pain Relevance 1.19

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signal transduction (Fgg) extracellular space (Fgg) extracellular region (Fgg)
protein binding, bridging (Fgg) molecular_function (Fgg) cellular_component (Fgg)
Anatomy Link Frequency
blood 2
Fgg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 14 99.28 Very High Very High Very High
Inflammation 2 94.44 High High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 14 99.28 Very High Very High Very High
Disorder Of Lipid Metabolism 2 98.40 Very High Very High Very High
Syndrome 14 98.28 Very High Very High Very High
INFLAMMATION 2 94.44 High High
Metabolic Disorder 2 93.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, fibrinogen beta chain, fibrinogen gamma chain, alpha1-antitrypsin, transthyretinc, haptoglobin beta chain, ApoA-IV, ApoA-I and haptoglobin alpha2 chain are differentially expressed in the patients with unstable angina blood-stasis syndrome and control group, some differentially expressed proteins were correlated with inflammatory reaction or lipid metabolic disorder, and these proteins could provide clues to the study and discovery of new protein targets for antianginal drugs.
Gene_expression (expressed) of fibrinogen gamma chain in blood associated with metabolic disorder, angina, inflammation and syndrome
1) Confidence 0.03 Published 2009 Journal Guang Pu Xue Yu Guang Pu Fen Xi Section Abstract Doc Link 19810551 Disease Relevance 1.40 Pain Relevance 0.60
Results show that fibrinogen beta chain, fibrinogen gamma chain, alpha1-antitrypsin, haptoglobin beta chain and haptoglobin alpha2 chain were significantly highly expressed in the plasma of unstable angina blood-stasis syndrome patient, while ApoA-IV, ApoA-I and transthyretin were decreased in the plasma of unstable angina blood-stasis syndrome patient.
Gene_expression (expressed) of fibrinogen gamma chain in blood associated with angina and syndrome
2) Confidence 0.03 Published 2009 Journal Guang Pu Xue Yu Guang Pu Fen Xi Section Abstract Doc Link 19810551 Disease Relevance 1.25 Pain Relevance 0.59

General Comments

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