INT163498

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.04
Pain Relevance 1.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Hcn3)
Anatomy Link Frequency
neurons 4
Hcn3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
hCN2 6 100.00 Very High Very High Very High
HCN1 4 100.00 Very High Very High Very High
c fibre 12 99.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 14 98.74 Very High Very High Very High
Ganglion Cysts 10 98.38 Very High Very High Very High
Diabetic Neuropathy 2 72.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared to the sham NG neurons, diabetes induced the expression of HCN2 in the A-fiber neurons besides overexpression of HCN1 and HCN3; and enhanced the expression of HCN2 and HCN3 in C-fiber neurons.
Positive_regulation (enhanced) of Gene_expression (expression) of HCN3 in neurons associated with ganglion cysts, c fibre, diabetes mellitus, hcn1 and hcn2
1) Confidence 0.68 Published 2010 Journal Neuroscience Section Abstract Doc Link 19815055 Disease Relevance 1.02 Pain Relevance 0.76
Compared to the sham NG neurons, diabetes induced the expression of HCN2 in the A-fiber neurons besides overexpression of HCN1 and HCN3; and enhanced the expression of HCN2 and HCN3 in C-fiber neurons.
Positive_regulation (overexpression) of Gene_expression (overexpression) of HCN3 in neurons associated with ganglion cysts, c fibre, diabetes mellitus, hcn1 and hcn2
2) Confidence 0.49 Published 2010 Journal Neuroscience Section Abstract Doc Link 19815055 Disease Relevance 1.02 Pain Relevance 0.75

General Comments

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