INT163618

Context Info Confidence 0.16 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.23 Pain Relevance 0.08

cytosol (Chuk, Rela) nucleus (Chuk, Rela) cytoplasm (Chuk, Rela) DNA binding (Rela) protein complex (Rela) transcription factor binding (Rela)

Anatomy Link Frequency neurons 1 Chuk (Mus musculus) Rela (Mus musculus)

Pain Link Frequency Relevance Heat dorsal root ganglion 1 80.88 TRP channel 2 75.00 qutenza 2 40.80 Calcium channel 1 33.44 sodium channel 2 25.00 c fibre 2 25.00 nociceptor 2 25.00 Nav1.6 1 25.00 Neuronal excitability 1 25.00

Disease Link Frequency Relevance Heat Ganglion Cysts 1 79.92 Nociception 2 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inhibitor kappaB kinase (IKK) regulates the activity of the transcription factor nuclear factor-kappa B that normally protects neurons against excitotoxicity.

IKK Regulation (regulates) of transcription factor nuclear factor-kappa B in neurons

1) Confidence 0.16 Published 2009 Journal J. Neurosci. Section Abstract Doc Link 19828806 Disease Relevance 0.23 Pain Relevance 0.08

General Comments

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