INT164322

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.57
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abcg2) ATPase activity (Abcg2) plasma membrane (Abcg2)
nucleus (Abcg2)
Anatomy Link Frequency
MCF-7 2
B-cell 1
Abcg2 (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 20 99.70 Very High Very High Very High
cINOD 4 97.84 Very High Very High Very High
Calcium channel 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 16 99.84 Very High Very High Very High
INFLAMMATION 4 97.64 Very High Very High Very High
Lymphatic System Cancer 2 97.60 Very High Very High Very High
Aging 1 90.76 High High
Obesity 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP cells expressed higher levels of the stem cell markers ATP-binding cassette transporter G2 (ABCG2), p75 neurotrophin receptor (p75NTR), nestin (nes), B-cell lymphoma 2 (Bcl2), and cell surface antigen Sca-1 mRNA than the main population cells.
Transcription (expressed) of ABCG2 in B-cell associated with lymphatic system cancer
1) Confidence 0.50 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2890558 Disease Relevance 0.19 Pain Relevance 0
Dexamethasone downregulates BCRP mRNA and protein expression in breast cancer cell lines.
Transcription (expression) of BCRP associated with breast cancer and dexamethasone
2) Confidence 0.26 Published 2009 Journal Oncol. Res. Section Title Doc Link 19911699 Disease Relevance 0.37 Pain Relevance 0.30
For evaluation of BCRP mRNA expression, relative quantitative PCR and comparative C1 method was exploited.
Transcription (expression) of BCRP
3) Confidence 0.26 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 19911699 Disease Relevance 0.34 Pain Relevance 0.25
Dexamethasone showed a dose-independent and a time-dependent effect on decreasing the mRNA level of BCRP gene in comparison with control in MCF-7 and MCF-7/MX breast cancer cell lines, whereas no changes were noted in the presence of indomethacin.
Transcription (level) of BCRP in MCF-7 associated with breast cancer and dexamethasone
4) Confidence 0.19 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 19911699 Disease Relevance 0.34 Pain Relevance 0.29
Dexamethasone showed a dose-independent and a time-dependent effect on decreasing the mRNA level of BCRP gene in comparison with control in MCF-7 and MCF-7/MX breast cancer cell lines, whereas no changes were noted in the presence of indomethacin.
Transcription (level) of BCRP in MCF-7 associated with breast cancer and dexamethasone
5) Confidence 0.06 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 19911699 Disease Relevance 0.34 Pain Relevance 0.29

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