INT164864

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 1.33
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8) signal transduction (Mapk8) mitochondrion (Mapk8)
nucleus (Mapk8) kinase activity (Mapk8) cytoplasm (Mapk8)
Anatomy Link Frequency
hepatocyte 3
liver 1
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 28 100.00 Very High Very High Very High
Analgesic 2 97.04 Very High Very High Very High
adenocard 2 70.72 Quite High
Disease Link Frequency Relevance Heat
Injury 6 100.00 Very High Very High Very High
Overdose 2 94.16 High High
Hepatotoxicity 6 88.04 High High
Stress 2 73.60 Quite High
Death 2 68.48 Quite High
Poisoning 2 45.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection.
Positive_regulation (induced) of Negative_regulation (inhibition) of JNK in hepatocyte associated with paracetamol and injury
1) Confidence 0.31 Published 2010 Journal Free Radic. Biol. Med. Section Title Doc Link 19969075 Disease Relevance 0.66 Pain Relevance 0.91
Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection.
Positive_regulation (induced) of in liver Negative_regulation (inhibition) of JNK in hepatocyte associated with paracetamol and injury
2) Confidence 0.11 Published 2010 Journal Free Radic. Biol. Med. Section Title Doc Link 19969075 Disease Relevance 0.66 Pain Relevance 0.91

General Comments

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