INT165845

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADCY1) small molecule metabolic process (ADCY1) plasma membrane (ADCY1)
nucleus (ADCY1) GTPase activity (ADCY1) transmembrane transport (ADCY1)
Anatomy Link Frequency
SK-N-SH 2
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 6 99.70 Very High Very High Very High
agonist 1 83.52 Quite High
Opioid 1 79.28 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 99.38 Very High Very High Very High
Shock 3 93.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In SK-N-SH human neuroblastoma cells, morphine significantly increased RNA transcript and protein levels of type I adenylate cyclase, leading to sensitization.
Positive_regulation (increased) of Transcription (transcript) of type I adenylate cyclase in SK-N-SH associated with neuroblastoma and morphine
1) Confidence 0.26 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20100459 Disease Relevance 0.36 Pain Relevance 0.55

General Comments

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