INT166390

Context Info Confidence 0.36 First Reported 2006 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 1.57 Pain Relevance 0.17

cytoplasm (CALB2)

CALB2 (Homo sapiens) CALB2 - D28K (1)

Pain Link Frequency Relevance Heat Neuropeptide 12 74.08 midbrain 2 73.00 Angina 1 71.64 Central nervous system 1 59.36 Neurotransmitter 95 50.00 substance P 11 22.72 Eae 6 13.96 gABA 44 5.00 Glutamate 22 5.00 Somatostatin 17 5.00

Disease Link Frequency Relevance Heat Cancer 11 98.86 Necrosis 1 98.50 Carcinoma 6 95.68 Disease 9 89.28 Lung Cancer 4 75.00 Malignant Neoplastic Disease 3 75.00 Angina 1 71.64 Neurodegenerative Disease 1 50.52 Ganglion Cysts 18 5.00 Hypertension 9 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Like calbindin (CalB), CALR is a calcium binding protein.

calbindin Binding (binding) of

1) Confidence 0.36 Published 2006 Journal J Circadian Rhythms Section Body Doc Link PMC1402333 Disease Relevance 0 Pain Relevance 0.04

Thus, the calcium-binding protein calbindin D28K is found in cells that are located in three ­layers of the mammalian SC [3, 23, 29, 31, 44].

calbindin D28K (D28K) Binding (binding) of

2) Confidence 0.35 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1698867 Disease Relevance 0.05 Pain Relevance 0.07

Histological findings showed necrosis and spindle tumor cells which were positive for AE1/AE3 and vimentin, and negative for calretinin, D2-40, and WT-1.

calretinin Binding (negative) of associated with necrosis and cancer

3) Confidence 0.26 Published 2010 Journal Nihon Kokyuki Gakkai Zasshi Section Abstract Doc Link 20163019 Disease Relevance 1.52 Pain Relevance 0.07

General Comments

This test has worked.