INT16657

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Context Info
Confidence 0.49
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (YY1) chromosome organization (YY1) RNA binding (YY1)
plasma membrane (YY1) nucleus (YY1) intracellular (YY1)
Anatomy Link Frequency
NG108-15 2
YY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Delta opioid receptors 2 100.00 Very High Very High Very High
Enkephalin 2 99.82 Very High Very High Very High
MU agonist 1 99.30 Very High Very High Very High
opioid receptor 3 94.08 High High
Potency 1 90.00 High High
agonist 3 88.80 High High
Opioid 2 56.80 Quite High
narcan 1 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Glioma 2 98.38 Very High Very High Very High
Neuroblastoma 2 98.20 Very High Very High Very High
Bordatella Infection 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic treatment of neuroblastoma x glioma NG108-15 hybrid cells with the opioid agonist D-Ala,2 D-Leu5-enkephalin (DADLE) induces a homologous desensitization of the delta opioid receptors present in these cells.
Positive_regulation (induces) of Negative_regulation (desensitization) of delta in NG108-15 associated with neuroblastoma, mu agonist, delta opioid receptors, enkephalin and glioma
1) Confidence 0.49 Published 1991 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1847209 Disease Relevance 0.42 Pain Relevance 0.55

General Comments

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