INT167588

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.24
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (HPS1) cytoplasmic membrane-bounded vesicle (HPS1) lysosome (HPS1)
cytoplasm (HPS1)
HPS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
reflex sympathetic dystrophy 2 100.00 Very High Very High Very High
Catechol-O-methyltransferase 109 98.84 Very High Very High Very High
Pain 23 97.28 Very High Very High Very High
alcohol 65 91.60 High High
tolerance 1 86.68 High High
addiction 11 81.60 Quite High
Inflammation 1 27.48 Quite Low
Catecholamine 7 25.44 Quite Low
drug abuse 9 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 78 100.00 Very High Very High Very High
Complex Regional Pain Syndromes 4 100.00 Very High Very High Very High
Pain 21 97.28 Very High Very High Very High
Poisoning 1 85.12 High High
Alcohol Addiction 2 81.60 Quite High
Schizophrenia 5 74.04 Quite High
Aggression 1 73.32 Quite High
Temporomandibular Joint Disorders 5 40.64 Quite Low
Hyperhomocysteinemia 2 31.16 Quite Low
Nutritional Deficiencies 1 29.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Despite the limitations, these findings indicate a need to educate HPs and students regarding substance use and abuse.
Localization (educate) of HPs
1) Confidence 0.65 Published 2008 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC2265282 Disease Relevance 0.17 Pain Relevance 0.35
Individuals exhibiting both the highest and lowest COMT activity were homozygous for the val158 allele, which is present in both the LPS and HPS haplotypes.
Localization (present) of HPS associated with catechol-o-methyltransferase and hantavirus infection
2) Confidence 0.46 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2664927 Disease Relevance 0.55 Pain Relevance 0.20
OBJECTIVES: Although the etiology of complex regional pain syndrome type 1 (CRPS 1) is still debated, many arguments favor central maladaptive changes in pain processing as an important causative factor.
Localization (etiology) of complex regional pain syndrome type 1 associated with complex regional pain syndromes, pain and reflex sympathetic dystrophy
3) Confidence 0.05 Published 2010 Journal Clin J Pain Section Abstract Doc Link 20393270 Disease Relevance 0.52 Pain Relevance 0.35

General Comments

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