INT168445

Context Info Confidence 0.14 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.66 Pain Relevance 0.46

extracellular region (C2, Dcn) extracellular space (Dcn) peptidase activity (C2) aging (Dcn) proteinaceous extracellular matrix (Dcn)

Anatomy Link Frequency central nervous system 3 C2 (Mus musculus) Dcn (Rattus norvegicus)

Pain Link Frequency Relevance Heat transcutaneous nerve stimulation 6 96.56 Central nervous system 1 96.56

Disease Link Frequency Relevance Heat Tinnitus 9 99.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

As electrical stimulation of C2 increases activation of the DCN through the somatosensory pathway and enlarges the inhibitory role of the DCN on the central nervous system, C2 TENS can be considered for tinnitus modulation.

Positive_regulation (stimulation) of C2 in central nervous system Positive_regulation (increases) of Positive_regulation (activation) of DCN in central nervous system associated with tinnitus, transcutaneous nerve stimulation and central nervous system

1) Confidence 0.14 Published 2010 Journal Exp Brain Res Section Abstract Doc Link 20505927 Disease Relevance 0.66 Pain Relevance 0.46

General Comments

This test has worked.