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Context Info
Confidence 0.47
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Cd38) plasma membrane (Cd38) nucleus (Cd38)
Cd38 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 9 99.32 Very High Very High Very High
antinociception 3 98.96 Very High Very High Very High
tolerance 6 98.16 Very High Very High Very High
Antinociceptive 2 92.88 High High
Potency 1 91.60 High High
Intracerebroventricular 2 89.28 High High
tail-flick 1 42.00 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 53.52 Quite High
Hypothermia 1 40.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study tested the hypothesis that the Ca(2+) signaling second messenger, cyclic ADP-ribose (cADPR), derived from CD38 activation participates in morphine antinociception and tolerance.
Positive_regulation (derived) of Positive_regulation (activation) of CD38 associated with antinociception, tolerance and morphine
1) Confidence 0.47 Published 2010 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 20551293 Disease Relevance 0.05 Pain Relevance 1.18

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