INT170444

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Context Info
Confidence 0.39
First Reported 2001
Last Reported 2011
Negated 7
Speculated 5
Reported most in Body
Documents 172
Total Number 177
Disease Relevance 45.05
Pain Relevance 20.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gopc) Golgi apparatus (Gopc) plasma membrane (Gopc)
cytoplasm (Gopc)
Anatomy Link Frequency
plaque 3
brain 3
neuronal 3
nerve 3
platelet 2
Gopc (Mus musculus)
Gopc - S129A (1)
Pain Link Frequency Relevance Heat
ketamine 386 100.00 Very High Very High Very High
Central nervous system 287 100.00 Very High Very High Very High
substance P 231 100.00 Very High Very High Very High
opioid receptor 195 100.00 Very High Very High Very High
cocaine 124 100.00 Very High Very High Very High
Peripheral nervous system 75 100.00 Very High Very High Very High
trigeminal ganglion 67 100.00 Very High Very High Very High
Infliximab 37 100.00 Very High Very High Very High
Etanercept 37 100.00 Very High Very High Very High
chemokine 472 99.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 851 100.00 Very High Very High Very High
Ganglion Cysts 194 100.00 Very High Very High Very High
Alzheimer's Dementia 118 100.00 Very High Very High Very High
Aids-related Complex 91 100.00 Very High Very High Very High
Mitral Valve Prolapse 72 100.00 Very High Very High Very High
Mevalonate Kinase Deficiency 58 100.00 Very High Very High Very High
INFLAMMATION 851 99.64 Very High Very High Very High
Porphyria 53 99.60 Very High Very High Very High
Nicotine Addiction 172 99.58 Very High Very High Very High
Injury 491 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that both the number of available vesicles and the release probability could be enhanced by inflammatory pain, whereas only the release probability could be enhanced by nerve ligation (Fig. 2C).


Fig Binding (ligation) of in vesicles associated with eae
1) Confidence 0.39 Published 2009 Journal Mol Pain Section Body Doc Link PMC2639542 Disease Relevance 0.43 Pain Relevance 0.77
The release probabilities in mice following CFA injection and mice with nerve ligation were also significantly increased (p < 0.05 and p < 0.05, respectively) in comparison with that in control mice, while there was no difference between those in mice following CFA injection and mice with nerve ligation (control, 0.67 ± 0.09, n = 12; CFA, 0.85 ± 0.07, n = 8; Nerve ligation, 0.90 ± 0.05, n = 9, Fig. 2B).
Fig Binding (ligation) of in Nerve
2) Confidence 0.39 Published 2009 Journal Mol Pain Section Body Doc Link PMC2639542 Disease Relevance 0.15 Pain Relevance 0.45
We used the experimental setup shown in Fig. 1
Fig Binding (shown) of
3) Confidence 0.32 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3017984 Disease Relevance 0.11 Pain Relevance 0.06
At the optimum condition in Fig. 7, where the Er:YAG emitted 200 ?
Fig Binding (condition) of
4) Confidence 0.32 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3017984 Disease Relevance 0 Pain Relevance 0
Although significant interactions between KT and psychostimulant treatments were not observed, recoveries shown in Fig. 2 were provided by KT in the COC and MA groups.


Fig Neg (not) Binding (interactions) of associated with ketamine and cocaine
5) Confidence 0.32 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1473192 Disease Relevance 0.58 Pain Relevance 0.54
Furthermore, significant interactions between treatments and test times were also observed, which indicated some time-dependent and KT dose-dependent changes shown in Fig. 1.


Fig Binding (interactions) of associated with ketamine
6) Confidence 0.32 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1473192 Disease Relevance 0.48 Pain Relevance 0.53
Alterations in toxic effects of high dose COC and MA (Fig. 4)
Fig Binding (Alterations) of associated with cocaine
7) Confidence 0.32 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1473192 Disease Relevance 0.30 Pain Relevance 0.55
Fig. 3Example main screen displayFig. 4Analyzed composite for a bubble frame (180 l DI water with 0.001% P2000, agitation 100 rpm, air flowrate 300 rpm) showing a original raw camera image, b binary image output with edge enhancement, c binary mask prior to application to image, d image after binary mask, e analysis output image containing colored circles identifying objects according to the three tiers of rules, and f instrument screen including histogram
Fig Binding (showing) of in edge
8) Confidence 0.32 Published 2007 Journal Bioprocess Biosyst Eng Section Body Doc Link PMC2214824 Disease Relevance 0 Pain Relevance 0
Fig. 3Example main screen displayFig. 4Analyzed composite for a bubble frame (180 l DI water with 0.001% P2000, agitation 100 rpm, air flowrate 300 rpm) showing a original raw camera image, b binary image output with edge enhancement, c binary mask prior to application to image, d image after binary mask, e analysis output image containing colored circles identifying objects according to the three tiers of rules, and f instrument screen including histogram
Fig Binding (according) of in edge
9) Confidence 0.32 Published 2007 Journal Bioprocess Biosyst Eng Section Body Doc Link PMC2214824 Disease Relevance 0 Pain Relevance 0
Fig. 3 corresponds to a series of internally initiated regular cycles over an extended period of time, with osteoclast and osteoblast populations exhibiting regular periodic cycles about their nontrivial steady state values (?
Fig Binding (corresponds) of in osteoblast associated with osteoporosis
10) Confidence 0.32 Published 2010 Journal Biol Direct Section Body Doc Link PMC2867965 Disease Relevance 0.27 Pain Relevance 0
The most distinctive differences between cetaceans and mice were found in the concentrations of plasma 3-MH and carnosine (Fig. 2).
Fig Binding (concentrations) of in plasma
11) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970564 Disease Relevance 0 Pain Relevance 0.05
The status by time interaction (Fig. 2) approached statistical significance (F(9, 423)?
Fig Binding (interaction) of
12) Confidence 0.31 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2613518 Disease Relevance 0.57 Pain Relevance 0.31
Using a social investigation (SI) paradigm, we found that the magnitude of SI by early-adolescent B6 mice was greater than that of age-matched BALB mice towards a novel F1 conspecific (similar to the object mice used during the pre-exposure sessions of the earlier experiments), although this strain difference was not maintained through late adolescence (Fig. 10a; genotype×age interaction, F[2,48]?
Fig Binding (interaction) of associated with sprains and strains
13) Confidence 0.31 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2633046 Disease Relevance 0.30 Pain Relevance 0
The rates of mEPSCs in mice following CFA injection and mice with nerve ligation were significantly larger (p < 0.01, respectively) than that in control mice (control, 1.1 ± 0.2 Hz, n = 12; CFA, 1.6 ± 0.3 Hz, n = 8; Nerve ligation, 1.9 ± 0.3 Hz, n = 9, Fig. 1E).
Fig Binding (ligation) of in nerve
14) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2639542 Disease Relevance 0 Pain Relevance 0.15
In contrast, TCNs exhibited a more gradual increase in mucin I-S adsorption and greater binding at 12 h than unmodified chitosan (Fig. 1c).


Fig Binding (binding) of
15) Confidence 0.29 Published 2006 Journal Respir Res Section Body Doc Link PMC1570356 Disease Relevance 0.12 Pain Relevance 0
Furthermore, addition of 100 nM ketanserin to the bath solution, a concentration that will antagonize both 5-HT2A and 5-HT2C receptors (Baxter et al., 1995) also did not prevent 5-HT from depolarizing (Fig. 2D) RIPCre neurons (5-HT, ?
Fig Binding (depolarizing) of in neurons
16) Confidence 0.29 Published 2009 Journal Neuroscience Section Body Doc Link PMC2661429 Disease Relevance 0 Pain Relevance 0.23
Double tissue immunoprocessing revealed that some of the virally labeled interneurons in lamina VII also co-expressed the calcium binding protein parvalbumin (PV; Fig. 6D and E).
Fig Binding (binding) of in lamina
17) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909228 Disease Relevance 0 Pain Relevance 0.12
Following nerve ligation, individual DRG glial cells showed neither morphological nor distributional change (Fig. 9C,D and 9G).
Fig Binding (ligation) of in nerve
18) Confidence 0.28 Published 2008 Journal Mol Pain Section Body Doc Link PMC2374773 Disease Relevance 0.08 Pain Relevance 0.04
or two (Fig. 2b, b?)
Fig Binding (two) of
19) Confidence 0.28 Published 2011 Journal Magnetic Resonance in Medicine Section Body Doc Link PMC3021721 Disease Relevance 0.08 Pain Relevance 0.08
-1a were recognized by the antibodies under non-reducing conditions (Fig. 2C).
Fig Binding (recognized) of
20) Confidence 0.28 Published 2010 Journal Pharm Res Section Body Doc Link PMC2916121 Disease Relevance 0 Pain Relevance 0

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