INT170747

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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2001
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2001|2001]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
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fontcolor=white,
 
fontcolor=white,
 
label="Binding",
 
label="Binding",
URL=Binding
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Binding"
 
];
 
];
 
node2
 
node2
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fontcolor=white,
 
fontcolor=white,
 
label="REM1",
 
label="REM1",
URL="REM1"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:28954"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
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{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[signal transduction]] ([[REM1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:signal transduction|signal transduction]] ([[G:28954|REM1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GTPase activity]] ([[REM1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:GTPase activity|GTPase activity]] ([[G:28954|REM1]])
 
|-
 
|-
 
|}
 
|}
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{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:233|nucleus]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:nucleus|nucleus]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Central nervous system]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Central nervous system|Central nervous system]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 87.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 87.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neurotransmitter]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Neurotransmitter|Neurotransmitter]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[substance P]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:substance P|substance P]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[dexamethasone]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:dexamethasone|dexamethasone]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[withdrawal]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:withdrawal|withdrawal]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 78.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 78.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[monoamine]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:monoamine|monoamine]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 70.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 70.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[antagonist]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:antagonist|antagonist]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 58.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 58.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Serotonin]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Serotonin|Serotonin]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[agonist]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:agonist|agonist]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 55.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 55.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[antidepressant]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:antidepressant|antidepressant]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 55.04
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 55.04
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Congenital Anomalies]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Congenital Anomalies|Congenital Anomalies]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Suicidal Behaviour]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Suicidal Behaviour|Suicidal Behaviour]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 344
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 344
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Schizophrenia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Schizophrenia|Schizophrenia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 202
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 202
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Aids-related Complex]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Aids-related Complex|Aids-related Complex]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 35
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 35
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cicatrix]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Cicatrix|Cicatrix]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 46.76
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 46.76
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Sleep Disorders]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Sleep Disorders|Sleep Disorders]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 35
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 35
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 34.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 34.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apnoea]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Apnoea|Apnoea]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 54
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 54
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Fever]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Fever|Fever]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28.56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28.56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Depression]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Depression|Depression]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 24.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 24.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Low}} {{#icon: cold.png|Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Low}} {{#icon: cold.png|Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Gagging]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Gagging|Gagging]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 23.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 23.96
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{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''REM'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">association</span>) of associated with <span style="color:#FF0000">'''suicidal behaviour'''</span>, <span style="color:#FF0000">'''congenital anomalies'''</span> and <span style="color:#FF0000">'''schizophrenia'''</span>
+
|  [[G:28954|<span style="color:#800000">'''REM'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">association</span>) of associated with <span style="color:#FF0000">'''suicidal behaviour'''</span>, <span style="color:#FF0000">'''congenital anomalies'''</span> and <span style="color:#FF0000">'''schizophrenia'''</span>
 
|-
 
|-
 
|}
 
|}
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Ann Gen Psychiatry|Ann Gen Psychiatry]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Ann Gen Psychiatry|Ann Gen Psychiatry]]
Line 270: Line 270:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''REM'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">associated</span>) of in <span style="color:#808000">nucleus</span>
+
|  [[G:28954|<span style="color:#800000">'''REM'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">associated</span>) of in [[A:nucleus|<span style="color:#808000">nucleus</span>]]
 
|-
 
|-
 
|}
 
|}
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.06
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.06
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2001
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2001|2001]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Respir Res|Respir Res]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Respir Res|Respir Res]]
Line 301: Line 301:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''REM'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">sleep</span>) of
+
|  [[G:28954|<span style="color:#800000">'''REM'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">sleep</span>) of
 
|-
 
|-
 
|}
 
|}
Line 312: Line 312:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:International Journal of Endocrinology|International Journal of Endocrinology]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:International Journal of Endocrinology|International Journal of Endocrinology]]
Line 332: Line 332:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''REM'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">seconds</span>) of
+
|  [[G:28954|<span style="color:#800000">'''REM'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">seconds</span>) of
 
|-
 
|-
 
|}
 
|}
Line 343: Line 343:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Frontiers in Neuroscience|Frontiers in Neuroscience]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Frontiers in Neuroscience|Frontiers in Neuroscience]]
Line 363: Line 363:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''REM'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">0.003</span>) of
+
|  [[G:28954|<span style="color:#800000">'''REM'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">0.003</span>) of
 
|-
 
|-
 
|}
 
|}
Line 374: Line 374:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.02
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.02
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]

Latest revision as of 14:04, 20 September 2012

Context Info
Confidence 0.10
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.65
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (REM1) GTPase activity (REM1)
Anatomy Link Frequency
nucleus 1
REM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 5 87.00 High High
Neurotransmitter 15 86.52 High High
substance P 6 84.32 Quite High
dexamethasone 1 82.00 Quite High
withdrawal 11 78.64 Quite High
monoamine 6 70.28 Quite High
antagonist 4 58.52 Quite High
Serotonin 15 56.64 Quite High
agonist 8 55.92 Quite High
antidepressant 6 55.04 Quite High
Disease Link Frequency Relevance Heat
Congenital Anomalies 2 99.72 Very High Very High Very High
Suicidal Behaviour 344 98.12 Very High Very High Very High
Schizophrenia 202 97.08 Very High Very High Very High
Aids-related Complex 35 86.48 High High
Cicatrix 1 46.76 Quite Low
Sleep Disorders 35 34.48 Quite Low
Apnoea 54 28.72 Quite Low
Fever 1 28.56 Quite Low
Depression 66 24.72 Low Low
Gagging 1 23.96 Low Low

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reports of an association between both REM sleep abnormalities and the results of the DST and suicidal behavior in schizophrenia have been reported [38,39].
REM Binding (association) of associated with suicidal behaviour, congenital anomalies and schizophrenia
1) Confidence 0.10 Published 2007 Journal Ann Gen Psychiatry Section Body Doc Link PMC1845151 Disease Relevance 1.49 Pain Relevance 0.07
This pharmacological REM-like state is also associated with reduced 5-HT at the hypoglossal motor nucleus [22].
REM Binding (associated) of in nucleus
2) Confidence 0.06 Published 2001 Journal Respir Res Section Body Doc Link PMC59518 Disease Relevance 0 Pain Relevance 0.12
Like REM sleep, the temporal pattern of SFA displays a robust circadian rhythm, with the peak of low-frequency SFA (12.25–13.00?
REM Binding (sleep) of
3) Confidence 0.05 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0 Pain Relevance 0.07
seconds for REM sleep, as total time spent in state within the past 30?
REM Binding (seconds) of
4) Confidence 0.03 Published 2007 Journal Frontiers in Neuroscience Section Body Doc Link PMC2577304 Disease Relevance 0.16 Pain Relevance 0.03
0.003 for REM; H?
REM Binding (0.003) of
5) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2699540 Disease Relevance 0 Pain Relevance 0.15

[edit] General Comments

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