INT170747

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Context Info
Confidence 0.10
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.65
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (REM1) GTPase activity (REM1)
Anatomy Mention Frequency
nucleus 1
REM1 (Homo sapiens)
Pain Term Frequency Confidence Heat
Central nervous system 5 87.00 High High
Neurotransmitter 15 86.52 High High
substance P 6 84.32 Quite High
dexamethasone 1 82.00 Quite High
withdrawal 11 78.64 Quite High
monoamine 6 70.28 Quite High
antagonist 4 58.52 Quite High
Serotonin 15 56.64 Quite High
agonist 8 55.92 Quite High
antidepressant 6 55.04 Quite High
Disease Term Frequency Confidence Heat
Congenital Anomalies 2 99.72 Very High Very High Very High
Suicidal Behaviour 344 98.12 Very High Very High Very High
Schizophrenia 202 97.08 Very High Very High Very High
Aids-related Complex 35 86.48 High High
Cicatrix 1 46.76 Quite Low
Sleep Disorders 35 34.48 Quite Low
Apnoea 54 28.72 Quite Low
Fever 1 28.56 Quite Low
Depression 66 24.72 Low Low
Gagging 1 23.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reports of an association between both REM sleep abnormalities and the results of the DST and suicidal behavior in schizophrenia have been reported [38,39].
REM Binding (association) of associated with suicidal behaviour, congenital anomalies and schizophrenia
1) Confidence 0.10 Published 2007 Journal Ann Gen Psychiatry Section Body Doc Link PMC1845151 Disease Relevance 1.49 Pain Relevance 0.07
This pharmacological REM-like state is also associated with reduced 5-HT at the hypoglossal motor nucleus [22].
REM Binding (associated) of in nucleus
2) Confidence 0.06 Published 2001 Journal Respir Res Section Body Doc Link PMC59518 Disease Relevance 0 Pain Relevance 0.12
Like REM sleep, the temporal pattern of SFA displays a robust circadian rhythm, with the peak of low-frequency SFA (12.25–13.00?
REM Binding (sleep) of
3) Confidence 0.05 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0 Pain Relevance 0.07
seconds for REM sleep, as total time spent in state within the past 30?
REM Binding (seconds) of
4) Confidence 0.03 Published 2007 Journal Frontiers in Neuroscience Section Body Doc Link PMC2577304 Disease Relevance 0.16 Pain Relevance 0.03
0.003 for REM; H?
REM Binding (0.003) of
5) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2699540 Disease Relevance 0 Pain Relevance 0.15

General Comments

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