INT171039

Context Info Confidence 0.05 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.26 Pain Relevance 0.33

plasma membrane (CD46)

CD46 (Homo sapiens)

Pain Link Frequency Relevance Heat dexamethasone 7 99.78 cytokine 44 96.88 chemokine 29 94.32 Inflammation 91 90.88 Inflammatory mediators 10 5.00 antagonist 7 5.00 Inflammatory response 5 5.00 cINOD 3 5.00 metalloproteinase 3 5.00 agonist 3 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 111 90.88 Asthma 41 84.28 Hypersensitivity 3 35.72 Injury 3 5.60 Airway Remodeling 13 5.00 Adhesions 9 5.00 Disease 5 5.00 Hyperplasia 4 5.00 Hypertrophy 4 5.00 Fibrosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, Pype et al. show that dexamethasone inhibited MCP mRNA expression and protein secretion in human ASM cells, whereas IL-10 had no effect on the expression [26].

Gene_expression (expression) of MCP mRNA associated with dexamethasone

1) Confidence 0.05 Published 2002 Journal Respir Res Section Body Doc Link PMC64809 Disease Relevance 0.26 Pain Relevance 0.33

General Comments

This test has worked.