INT172137

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Context Info
Confidence 0.09
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL11, TNF) extracellular region (IL11, TNF) signal transduction (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
synovium 2
IL11 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 88 98.98 Very High Very High Very High
Arthritis 37 73.44 Quite High
cytokine 53 72.68 Quite High
chemokine 4 61.16 Quite High
Inflammation 37 58.96 Quite High
fibrosis 1 46.80 Quite Low
antagonist 10 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 91 98.98 Very High Very High Very High
Arthritis 36 73.44 Quite High
Experimental Arthritis 6 63.72 Quite High
INFLAMMATION 37 58.96 Quite High
Fibrosis 1 46.80 Quite Low
Autoimmune Disease 3 38.84 Quite Low
Hypercalcemia 2 27.08 Quite Low
Severe Combined Immunodeficiency 2 11.68 Low Low
Disease 20 5.00 Very Low Very Low Very Low
Synovitis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
production in RA synovium in vitro [98], whereas recombinant human IL-11 reduces the production of TNF-?
IL-11 Negative_regulation (reduces) of Gene_expression (production) of TNF in synovium associated with rheumatoid arthritis
1) Confidence 0.09 Published 2000 Journal Arthritis Res Section Body Doc Link PMC130001 Disease Relevance 0.73 Pain Relevance 0.47

General Comments

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