INT172593

Context Info Confidence 0.36 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.05 Pain Relevance 0.04

extracellular space (EMR3) extracellular region (EMR3) plasma membrane (EMR3) signal transducer activity (EMR3)

Anatomy Link Frequency immune system 2 EMR3 (Homo sapiens)

Pain Link Frequency Relevance Heat Neurotransmitter 2 81.36 Glutamate receptor 4 5.00 Hippocampus 4 5.00 long-term potentiation 2 5.00 Spinal cord 2 5.00 Inflammation 2 5.00 Pain 2 5.00 agonist 2 5.00 Eae 2 5.00

Disease Link Frequency Relevance Heat Glioblastoma 2 50.72 Congenital Anomalies 8 5.00 Chondrodysplasia 6 5.00 Adhesions 4 5.00 Aging 4 5.00 Stress 4 5.00 Targeted Disruption 4 5.00 Hypercalcemia 2 5.00 Kidney Stones 2 5.00 Inflammatory Bowel Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CD97 is the only receptor in subfamily B2 for which the ligand has so far been identified, although there is evidence for the existence of a ligand for EMR3, another member of subfamily B2 expressed in the immune system, on human macrophages and activated neutrophils [27].

Gene_expression (expressed) of EMR3 in immune system

1) Confidence 0.36 Published 2001 Journal Genome Biol Section Body Doc Link PMC138994 Disease Relevance 0 Pain Relevance 0

EMR1 and CD97 are closely related in structure to two other human proteins (EMR2 and EMR3), and all members of this group are highly expressed in the immune system.

Gene_expression (expressed) of EMR3 in immune system

2) Confidence 0.28 Published 2001 Journal Genome Biol Section Body Doc Link PMC138994 Disease Relevance 0.05 Pain Relevance 0.04

General Comments

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