INT172597

Context Info Confidence 0.01 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0.20

cell differentiation (ADCYAP1R1) endosome (ADCYAP1R1) plasma membrane (ADCYAP1R1) cytoplasm (ADCYAP1R1) signal transducer activity (ADCYAP1R1)

Anatomy Link Frequency dentate gyrus 1 ADCYAP1R1 (Homo sapiens)

Pain Link Frequency Relevance Heat Hippocampus 2 96.32 Spinal cord 1 95.40 long-term potentiation 1 65.44 Eae 1 62.48 Pain 1 48.16 Glutamate receptor 2 5.00 Inflammation 1 5.00 Neurotransmitter 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Congenital Anomalies 4 75.36 Anxiety Disorder 1 60.24 Chondrodysplasia 3 5.00 Adhesions 2 5.00 Aging 2 5.00 Stress 2 5.00 Targeted Disruption 2 5.00 Hypercalcemia 1 5.00 Kidney Stones 1 5.00 Inflammatory Bowel Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, the PAC1 receptor is widely distributed in the central and peripheral nervous systems, most abundantly in the dentate gyrus of the hippocampus and in the spinal cord, but is also expressed in pancreatic beta (insulin-secreting) cells.

Positive_regulation (distributed) of PAC1 receptor in dentate gyrus associated with hippocampus and spinal cord

1) Confidence 0.01 Published 2001 Journal Genome Biol Section Body Doc Link PMC138994 Disease Relevance 0.14 Pain Relevance 0.20

General Comments

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