INT173106

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Context Info
Confidence 0.44
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
proteinaceous extracellular matrix (VEGFA) nucleus (Fos) DNA binding (Fos)
Anatomy Link Frequency
Capan-1 1
VEGFA (Homo sapiens)
Fos (Mus musculus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 81.84 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 81 92.44 High High
Pancreatitis 3 81.84 Quite High
Cancer 77 79.36 Quite High
Recurrence 2 53.28 Quite High
Hypoxia 50 50.00 Quite Low
Metastasis 25 49.44 Quite Low
Pressure And Volume Under Development 1 28.56 Quite Low
Malignant Neoplastic Disease 4 19.12 Low Low
Adenocarcinoma 10 5.00 Very Low Very Low Very Low
Solid Tumor 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional receptor binding studies by this group confirmed high levels of VEGF-VEGFR interaction only in Capan-1 cells; VEGF dose-dependently enhanced proliferation, promoted MAPK phosphorylation, and induced c-fos activity only in these Capan-1 cells [82].
VEGF Positive_regulation (induced) of c-fos in Capan-1
1) Confidence 0.44 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.64 Pain Relevance 0.08

General Comments

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