INT173114

From wiki-pain
Revision as of 03:20, 22 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2002
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 2.56
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
Anatomy Link Frequency
lung 2
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 92 99.82 Very High Very High Very High
Nerve growth factor 54 95.64 Very High Very High Very High
Inflammation 95 94.84 High High
substance P 13 94.80 High High
chemokine 5 94.28 High High
agonist 24 90.16 High High
Pain 32 86.64 High High
Neuropeptide 10 85.60 High High
Arthritis 13 73.40 Quite High
antagonist 16 73.28 Quite High
Disease Link Frequency Relevance Heat
Lung Injury 2 99.74 Very High Very High Very High
Immunization 1 97.04 Very High Very High Very High
INFLAMMATION 101 94.84 High High
Mycobacterial Infection 19 93.32 High High
Nociception 6 92.40 High High
Pain 27 86.64 High High
Critical Illness 1 83.76 Quite High
Chondrosarcoma 6 83.68 Quite High
Adhesions 26 77.28 Quite High
Disease 75 77.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previously, we determined that simultaneous treatment with IL-1?
Spec (determined) Positive_regulation (simultaneous) of IL-1 Spec (determined) Binding (treatment) of
1) Confidence 0.49 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0.23 Pain Relevance 0.12
The severity of lung injury seems to be related negatively with BALF IL-1, TNF-?
Positive_regulation (negatively) of BALF IL-1 Binding (related) of in lung associated with lung injury
2) Confidence 0.32 Published 2002 Journal Respir Res Section Body Doc Link PMC150513 Disease Relevance 0.53 Pain Relevance 0.15
The antibody was initially identified from a hybridoma derived from these mice because of its ability to bind human IL-1?
Positive_regulation (derived) of IL-1 Binding (bind) of
3) Confidence 0.12 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483458 Disease Relevance 0.10 Pain Relevance 0.10
A report indicates that sIL-1RAcP associates as ligand-bound to type II sIL-1R, increasing the binding affinity of IL-1?
Positive_regulation (increasing) of IL-1 Binding (affinity) of
4) Confidence 0.10 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526599 Disease Relevance 0.25 Pain Relevance 0.07
on neurotrophin expression in the IVD also requires the presence of IL-1?
Positive_regulation (requires) of IL-1 Binding (presence) of
5) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575613 Disease Relevance 0.50 Pain Relevance 0.47
Cytokines such as IL-1 can also stimulate the NFkB binding molecule to activate NFkB [54-56], which induces the expression of cyclooxygenase-2 (COX-2), which consequently leads to tissue inflammation at the site where latent TB antigens are located.
Positive_regulation (stimulate) of IL-1 Binding (binding) of associated with mycobacterial infection, inflammation and cytokine
6) Confidence 0.09 Published 2007 Journal AIDS Res Ther Section Body Doc Link PMC2216023 Disease Relevance 0.87 Pain Relevance 0.23
secretion, without the loss of membrane asymmetry, whereas a subsequent hit with ATP drives a rapid amplification of IL-1?
Positive_regulation (drives) of IL-1 Binding (amplification) of
7) Confidence 0.09 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox