INT173704

Context Info Confidence 0.01 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.99 Pain Relevance 0.37

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1) cytoplasm (Edn1)

Anatomy Link Frequency sympathetic 1 PCOS1 (Homo sapiens) Edn1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Nerve growth factor 59 99.12 Acupuncture 57 81.92 Spinal cord 6 5.00 Central nervous system 6 5.00 c fibre 1 5.00 Neuropeptide 1 5.00 Catecholamine 1 5.00

Disease Link Frequency Relevance Heat Polycystic Ovary Syndrome 64 100.00 Increased Venous Pressure Under Development 1 89.84 Anovulation 2 74.48 Congenital Anomalies 1 60.12 Follicular Cyst 3 59.68 Syndrome 1 45.24 Endocrine Disease 1 40.72 Stress 3 5.00 Hyperinsulinism 1 5.00 Cyst 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This finding supports the theories of a link between ET-1 and increased sympathetic nerve activity associated with PCOS in women.

PCOS Binding (associated) of ET-1 in sympathetic associated with polycystic ovary syndrome

1) Confidence 0.01 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC155675 Disease Relevance 0.99 Pain Relevance 0.37

General Comments

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