INT173922

Context Info Confidence 0.30 First Reported 2003 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.20 Pain Relevance 0.19

Anatomy Link Frequency NK cell 2 CD69 (Homo sapiens)

Pain Link Frequency Relevance Heat Osteoarthritis 14 82.92 Inflammation 36 75.56 rheumatoid arthritis 35 73.44 cytokine 33 5.00 Inflammatory response 3 5.00 depression 2 5.00 Bile 2 5.00 Inflammatory mediators 2 5.00 tolerance 2 5.00 Crohn's disease 2 5.00

Disease Link Frequency Relevance Heat Disease 17 92.08 Cancer 12 89.20 Systemic Sclerosis 14 86.64 Osteoarthritis 14 82.92 Systemic Lupus Erythematosus 18 76.24 INFLAMMATION 40 75.56 Rheumatoid Arthritis 35 73.44 Autoimmune Disease 17 71.68 Thyroiditis 2 54.40 Nephritis 3 48.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In order to investigate a possible effect of MTB and CW on NK cell activation, we examined changes in expression of the NK activation cell surface marker CD69.

Spec (examined) Regulation (changes) of Gene_expression (expression) of CD69 in NK cell

1) Confidence 0.30 Published 2010 Journal BMC Immunol Section Body Doc Link PMC2858026 Disease Relevance 0.16 Pain Relevance 0.04

Plasmid construction for the expression of recombinant LRP2 and CD69 molecules

Regulation (molecules) of Gene_expression (expression) of CD69

2) Confidence 0.22 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC165049 Disease Relevance 1.04 Pain Relevance 0.16

General Comments

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