INT173967

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Context Info
Confidence 0.43
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 26
Total Number 26
Disease Relevance 16.67
Pain Relevance 6.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Mri1) nucleus (Mri1) cytoplasm (Mri1)
Anatomy Link Frequency
brain 3
macrophages 1
spinal 1
Artery 1
cranial 1
Mri1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1321 100.00 Very High Very High Very High
Pain 24 97.24 Very High Very High Very High
Spinal cord 23 96.92 Very High Very High Very High
corticosteroid 40 95.76 Very High Very High Very High
Analgesic 19 95.28 Very High Very High Very High
anesthesia 9 94.04 High High
fifth nerve 2 92.64 High High
Inflammation 166 87.36 High High
trigeminal ganglion 2 86.32 High High
fibrosis 7 77.68 Quite High
Disease Link Frequency Relevance Heat
Congenital Anomalies 55 99.96 Very High Very High Very High
Cancer 1194 99.54 Very High Very High Very High
Sprains And Strains 19 99.38 Very High Very High Very High
Residual Neoplasm 23 99.36 Very High Very High Very High
Glioblastoma 47 99.28 Very High Very High Very High
Phobia 5 98.84 Very High Very High Very High
Paraparesis 2 98.84 Very High Very High Very High
Meningioma 91 98.62 Very High Very High Very High
Pancreatic Cancer 21 98.52 Very High Very High Very High
Stroke 138 98.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These chronic progressive cranial MRI abnormalities have been also observed in an experimental mouse model of HSVE [8].
Gene_expression (progressive) of MRI in cranial associated with congenital anomalies, viral meningitis and imagery
1) Confidence 0.43 Published 2008 Journal BMC Neurol Section Body Doc Link PMC2605746 Disease Relevance 0.82 Pain Relevance 0.31
All patients tolerated the MRI-guided FUS procedure well, and only one minor complication, a skin burn, was reported.
Gene_expression (procedure) of MRI-guided in skin associated with burns and imagery
2) Confidence 0.40 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.13 Pain Relevance 0.63
Although the results of US-guided and MRI-guided FUS ablation are promising, the data are too scant to justify a randomized controlled trial that compares FUS ablation with breast-conserving surgery for treatment of localized breast cancer.
Gene_expression (ablation) of MRI-guided associated with breast cancer and imagery
3) Confidence 0.40 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.08 Pain Relevance 0.25
Histopathological analyses following MRI-gFUS showed no residual cancer in 8 lesions (31%), less than 10% in 11 lesions (42%) and between 20–90% in 7 lesions (27%).
Gene_expression (following) of MRI associated with residual neoplasm and imagery
4) Confidence 0.40 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.33 Pain Relevance 0.30
For MRI-guided FUS ablation, it is also required that, apart from the standard MRI contra-indication, patients must lie still in the closed bore MRI magnet for a long period of time, which can be physically and psychologically difficult, especially in anxious or claustrophobic patients [27].
Gene_expression (ablation) of MRI-guided associated with imagery
5) Confidence 0.40 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.04 Pain Relevance 0.21
In general, this percentage clearly exceeds the success percentage of MRI-guided FUS ablation, although MRI is expected to be the most reliable imaging modality for breast cancer detection and delineation.
Gene_expression (expected) of MRI associated with breast cancer and imagery
6) Confidence 0.40 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.22 Pain Relevance 0.18
MPIO Binding in the Femoral Artery by ex vivo MRI
Gene_expression (by) of MRI in Artery associated with imagery
7) Confidence 0.29 Published 2009 Journal Journal of Vascular Research Section Body Doc Link PMC2914450 Disease Relevance 0 Pain Relevance 0.05
OKB, MVE, CL, MRH performed MRI experiments.
Gene_expression (experiments) of MRI
8) Confidence 0.17 Published 2009 Journal Mol Brain Section Body Doc Link PMC2785804 Disease Relevance 0.35 Pain Relevance 0.08
MRI analysis
Gene_expression (analysis) of MRI associated with imagery
9) Confidence 0.15 Published 2007 Journal Cardiovasc Diabetol Section Body Doc Link PMC1805425 Disease Relevance 0 Pain Relevance 0.05
MRI analysis
Gene_expression (analysis) of MRI associated with imagery
10) Confidence 0.15 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2978145 Disease Relevance 0.67 Pain Relevance 0.22
At this concentration and MRI voxel size of 0.09 mm3 (300 µm×300 µm×1 mm) used in this study, 9 FE-Pro labeled cells would produce detectable MRI signal reduction.
Gene_expression (produce) of MRI associated with imagery
11) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.37 Pain Relevance 0.17
Sham injection (PBS), contralateral to the tumor implants (Fig. 4C) resulted in no hypointense signal in MRI images and correlated with a lack of PB staining in these histological samples (Fig. 4D).
Gene_expression (images) of MRI associated with cancer and imagery
12) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.64 Pain Relevance 0.26
At this concentration and MRI voxel size of 0.09 mm3 (300 µm×300 µm×1 mm) used in this study, 9 FE-Pro labeled cells would produce detectable MRI signal reduction.
Gene_expression (produce) of MRI associated with imagery
13) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.36 Pain Relevance 0.18
A fraction of NSCs that migrated to the tumor implant in the opposite hemisphere were visible at 600 FE-Pro-labeled NSCs per site with an MRI resolution of 76 µm×76 µm×300 µm.
Gene_expression (resolution) of MRI associated with cancer and imagery
14) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.42 Pain Relevance 0.38
It has been reported that even a single cell can be tracked in MRI in case of highly phagocytic, large cells, such as macrophages [53].
Gene_expression (tracked) of MRI in macrophages associated with imagery
15) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.55 Pain Relevance 0.36
For estimation of the number of FePro-labeled cells detectable by ex vivo MRI in mouse brain, we collected thirty 10-µm thick sections from the brain, and randomly selected 6 sections that spanned 300 µm of distance corresponding to MRI image in Fig. 5A.
Gene_expression (detectable) of MRI in brain associated with imagery
16) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0 Pain Relevance 0.25
For estimation of the number of FePro-labeled cells detectable by ex vivo MRI in mouse brain, we collected thirty 10-µm thick sections from the brain, and randomly selected 6 sections that spanned 300 µm of distance corresponding to MRI image in Fig. 5A.
Gene_expression (image) of MRI in brain associated with imagery
17) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0 Pain Relevance 0.24
A concern is the possible false positive interpretation of the MRI signal, which may be produced by macrophages that have engulfed non-viable labeled NSCs or freely-dispersed iron nanoparticles in the brain tissue [54].
Gene_expression (produced) of MRI in brain associated with imagery
18) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.38 Pain Relevance 0.32
Manon and colleagues have shown that mid treatment MRI imaging in patients with GBM may allow for improved target delineation for the boost volumes (Manon et al 2004).
Gene_expression (imaging) of MRI in GBM associated with glioblastoma and imagery
19) Confidence 0.07 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673824 Disease Relevance 0.76 Pain Relevance 0.18
Age and strain controls were matched for the MRI studies as for all other studies in this manuscript.


Gene_expression (studies) of MRI associated with sprains and strains
20) Confidence 0.07 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2588578 Disease Relevance 1.25 Pain Relevance 0

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