INT175464

Context Info Confidence 0.19 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.05 Pain Relevance 0.20

cell differentiation (Hand2) extracellular space (Sftpd) extracellular region (Sftpd) proteinaceous extracellular matrix (Sftpd) nucleus (Hand2) DNA binding (Hand2)

Anatomy Link Frequency lung 2 Hand2 (Mus musculus) Sftpd (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 20 100.00 Inflammatory response 2 14.36 cytokine 14 5.00 ketamine 1 5.00 anesthesia 1 5.00 isoflurane 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 21 100.00 Hypersensitivity 35 99.98 Aspergillus Infection 44 97.16 Asthma 5 88.08 Pneumonia 2 83.52 Pneumocystis Pneumonia 1 74.80 Injury 1 27.36 Disease 1 23.00 Sprains And Strains 16 5.00 Eosinophilia 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We have previously shown that allergic Th2-type inflammation induced production of SP-D, an otherwise constitutively expressed protein in the lung [12].

Th2-type Positive_regulation (induced) of Gene_expression (production) of SP-D in lung associated with inflammation and hypersensitivity

1) Confidence 0.19 Published 2003 Journal Respir Res Section Body Doc Link PMC314399 Disease Relevance 1.05 Pain Relevance 0.20

General Comments

This test has worked.