INT175727

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1B, VEGFA) extracellular region (IL1B, VEGFA) aging (IL1B)
cytoplasm (VEGFA) cell-cell signaling (IL1B) cytosol (IL1B)
Anatomy Link Frequency
lymphatic vessels 1
IL1B (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 13 99.66 Very High Very High Very High
Pain 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Helminth Infection 60 84.60 Quite High
Death 4 70.72 Quite High
Hydrocele 12 65.76 Quite High
Lymphedema 77 59.28 Quite High
Hypertrophy 2 54.72 Quite High
Disease 19 53.28 Quite High
Glycogen Storage Disease 1 45.08 Quite Low
Diabetes Mellitus 4 41.80 Quite Low
Cancer 8 36.48 Quite Low
Obesity 2 30.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the vascular endothelial growth factor gene (Vegf) [50], which is also regulated by IL-1, had the highest fold change at 18 hours after RE (1.6-fold).
IL-1 Regulation (regulated) of Vegf
1) Confidence 0.04 Published 2003 Journal Genome Biol Section Body Doc Link PMC328450 Disease Relevance 0.05 Pain Relevance 0
This raises the possibility that proinflammatory cytokines such as TNF and IL-1B induced by Wolbachia could affect lymphatic vessels via VEGF-C and its receptor sVEGFR-3.
IL-1B Regulation (affect) of VEGF in lymphatic vessels associated with cytokine
2) Confidence 0.00 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1564427 Disease Relevance 0.65 Pain Relevance 0.19

General Comments

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