INT176629

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Context Info
Confidence 0.10
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 6.89
Pain Relevance 1.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GREM1) extracellular region (GREM1) cell-cell signaling (GREM1)
Anatomy Link Frequency
nasal 1
respiratory 1
GREM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 22 99.84 Very High Very High Very High
Inflammatory response 5 98.66 Very High Very High Very High
rheumatoid arthritis 225 98.04 Very High Very High Very High
Osteoarthritis 81 97.76 Very High Very High Very High
Inflammation 46 95.04 Very High Very High Very High
Inflammatory mediators 14 91.68 High High
antagonist 24 86.44 High High
metalloproteinase 14 83.84 Quite High
cocaine 8 39.12 Quite Low
interstitial cystitis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 141 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 29 100.00 Very High Very High Very High
Influenza Virus Infection 69 99.38 Very High Very High Very High
Adhesions 228 99.24 Very High Very High Very High
Recurrence 6 99.14 Very High Very High Very High
INFLAMMATION 65 98.48 Very High Very High Very High
Rheumatoid Arthritis 225 98.04 Very High Very High Very High
Osteoarthritis 81 97.76 Very High Very High Very High
Hepatitis B Virus Infection 15 97.68 Very High Very High Very High
Cancer 17 94.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The rate of HIV infection among IDU in Australia is probably too low to produce dramatic increases in the number of HIV infections in that time, even if the risk of infection was increased [42].
Gene_expression (produce) of increased associated with acquired immune deficiency syndrome or hiv infection and infection
1) Confidence 0.10 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1199605 Disease Relevance 1.35 Pain Relevance 0
The inflammatory response is characterized by the activation of cellular mechanisms and the increased production of cytokines like interleukin 1?
Gene_expression (production) of increased associated with inflammatory response and cytokine
2) Confidence 0.02 Published 2004 Journal BMC Musculoskelet Disord Section Body Doc Link PMC404466 Disease Relevance 0.69 Pain Relevance 0.27
Similarly, p53 protein expression was also increased in response to APF in cells transfected with non-target siRNA, whereas p53 levels changed less in response to APF following CKAP4 knockdown (Figure 2A). qRT-PCR also showed significantly increased p53 mRNA expression following APF treatment of nontransfected or non-target siRNA-transfected, but not CKAP4 siRNA-transfected, cells (Figure 2B-D) (p < .01 for both nontransfected and non-target transfected cells, and target gene mRNA relative to ?
Gene_expression (expression) of increased
3) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3020166 Disease Relevance 0.22 Pain Relevance 0
The expression of several integrin-receptor subunits is also increased in situ.
Gene_expression (expression) of increased
4) Confidence 0.01 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991025 Disease Relevance 1.05 Pain Relevance 0.46
Increased levels of fibronectin have been found in rheumatoid synovial tissues [23-25].
Gene_expression (levels) of Increased
5) Confidence 0.01 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991025 Disease Relevance 0.85 Pain Relevance 0.36
After 2-hour adhesion, 10-7 M adrenomedullin significantly increased the expression of the ?
Gene_expression (expression) of increased associated with adhesions
6) Confidence 0.01 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991025 Disease Relevance 0.54 Pain Relevance 0.23
Similarly, experimental infection of 17 adult volunteers with influenza A virus induced significantly increased levels of IL-6, but not IL-4, in nasal lavage fluids of all 12 subjects who shed virus [58].
Gene_expression (levels) of increased in nasal associated with influenza virus infection and infection
7) Confidence 0.01 Published 2010 Journal J Leukoc Biol Section Body Doc Link PMC2812561 Disease Relevance 0.92 Pain Relevance 0.21
Conversely, influenza A virus infection, which also leads to an increased production of respiratory secretions in the 1st week after exposure of human volunteers [107], does indeed alter the character of these respiratory fluids.
Gene_expression (production) of increased in respiratory associated with influenza virus infection and infection
8) Confidence 0.01 Published 2010 Journal J Leukoc Biol Section Body Doc Link PMC2812561 Disease Relevance 0.46 Pain Relevance 0
Treatment failure that occurred after 2–5 days of compliance with either of two antibiotic regimens was significantly associated with greater LTB4 levels in initial MEFs, whereas recurrence of AOM within 1 month was associated with increased IL-8 levels in these effusions.
Gene_expression (levels) of increased associated with recurrence
9) Confidence 0.01 Published 2010 Journal J Leukoc Biol Section Body Doc Link PMC2812561 Disease Relevance 0.80 Pain Relevance 0.14

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