INT177941

From wiki-pain
Revision as of 03:55, 22 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.31
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAP3K1) cytoskeleton (MAP3K1) cytoplasm (MAP3K1)
Anatomy Link Frequency
TK-1 1
MAP3K1 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 48 86.16 High High
Inflammation 1 73.72 Quite High
imagery 37 61.92 Quite High
cINOD 6 49.96 Quite Low
peripheral neuropathy 5 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 28 94.40 High High
Apoptosis 37 92.88 High High
Colon Cancer 1 89.60 High High
Toxicity 18 79.08 Quite High
INFLAMMATION 3 73.72 Quite High
Lung Cancer 5 72.60 Quite High
Familial Adenomatous Polyposis 5 55.12 Quite High
Polyps 1 52.44 Quite High
Recurrence 2 51.28 Quite High
Nerve Sheath Neoplasms 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, PKG activates the JNK pathway via phosphorylation and activation of MEKK1 [21,22].
Phosphorylation (phosphorylation) of MEKK1
1) Confidence 0.20 Published 2004 Journal Cancer Cell Int Section Body Doc Link PMC425591 Disease Relevance 1.01 Pain Relevance 0.04
FLT, a thymidine nucleoside analog, undergoes the same first metabolic step as thymidine when it is 5'-monophosphorylated by the cytosolic enzyme thymidine kinase-1 (TK-1), however, the 3' substitution prevents further incorporation into DNA.
Phosphorylation (monophosphorylated) of kinase-1 in TK-1
2) Confidence 0.05 Published 2007 Journal BMC Nucl Med Section Body Doc Link PMC1931583 Disease Relevance 0.30 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox