INT178591

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Context Info
Confidence 0.23
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.56
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CNTN2) plasma membrane (CNTN2)
CNTN2 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 83 94.36 High High
Arthritis 13 84.80 Quite High
cytokine 26 72.56 Quite High
Osteoarthritis 45 70.76 Quite High
Inflammation 25 68.32 Quite High
rheumatoid arthritis 17 51.40 Quite High
Hippocampus 7 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Sciatic nerve 4 5.00 Very Low Very Low Very Low
iatrogenic 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Contagious Ecthyma 10 93.00 High High
Infection 68 92.36 High High
Glioma 6 90.16 High High
Disease 45 87.72 High High
Cancer 64 85.68 High High
Arthritis 17 84.80 Quite High
Syndrome 45 84.04 Quite High
Apoptosis 36 73.48 Quite High
Frailty 46 70.76 Quite High
Limbic Encephalitis 27 69.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, direct binding of Tax to the nuclear factor-?
Tax Binding (binding) of
1) Confidence 0.23 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC464878 Disease Relevance 0.71 Pain Relevance 0.30
The oncogenic potential of Tax can be dissociated from its transcriptional activation potential by specific mutations.
Tax Binding (dissociated) of
2) Confidence 0.13 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.16 Pain Relevance 0.03
However, some proviruses harboring deletions in the central portion of the genome do not contain the second exon required for initiation of Tax.
Tax Binding (initiation) of
3) Confidence 0.13 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.24 Pain Relevance 0
Five sera bound to contactin-2 itself but four of these sera also bound to Kv1, Caspr2 or Lgi1.


contactin-2 Binding (bound) of
4) Confidence 0.07 Published 2010 Journal Brain Section Body Doc Link PMC2929337 Disease Relevance 0.45 Pain Relevance 0.11

General Comments

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