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Context Info
Confidence 0.75
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.05
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp1a2) endoplasmic reticulum (Cyp1a2) enzyme binding (Cyp1a2)
response to stress (Cyp1a2)
Anatomy Link Frequency
liver 1
Cyp1a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Duloxetine 84 99.92 Very High Very High Very High
Paracetamol 1 94.52 High High
fluoxetine 1 92.88 High High
Bile 1 79.40 Quite High
anesthesia 1 76.72 Quite High
Desipramine 3 48.32 Quite Low
monoamine 2 46.60 Quite Low
sSRI 2 45.92 Quite Low
Nortriptyline 1 36.40 Quite Low
Endep 3 35.20 Quite Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 1 53.60 Quite High
Diabetes Mellitus 12 50.00 Quite Low
Fungal Infection 1 38.32 Quite Low
Arrhythmia Under Development 1 18.64 Low Low
Pain 51 5.00 Very Low Very Low Very Low
Neuropathic Pain 19 5.00 Very Low Very Low Very Low
Diabetic Neuropathy 15 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 5 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: biliary excretion and induction of cytochromes CYP1A1 and CYP1A2.
Localization (excretion) of CYP1A2
1) Confidence 0.75 Published 1991 Journal Toxicol. Appl. Pharmacol. Section Title Doc Link 1949032 Disease Relevance 0 Pain Relevance 0.12
Collectively, BF has inducing potential of liver CYP1A2 and CYP2E1 and may influence the corresponding pharmacokinetics of other drugs.
Localization (potential) of CYP1A2 in liver
2) Confidence 0.71 Published 2010 Journal J Asian Nat Prod Res Section Abstract Doc Link 20496194 Disease Relevance 0.05 Pain Relevance 0.09
Drugs metabolized by CYP1A2
Localization (metabolized) of CYP1A2
3) Confidence 0.63 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350145 Disease Relevance 0 Pain Relevance 0.54

General Comments

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