INT179037

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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.52
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Fez1) mitochondrion (Fez1) plasma membrane (Fez1)
cytoskeleton (Fez1) cytoplasm (Fez1)
Anatomy Link Frequency
lymph node 3
Fez1 (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 8 60.80 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
pain flank 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 40 99.40 Very High Very High Very High
Cancer 184 94.84 High High
Carcinoma 140 80.68 Quite High
Solid Tumor 12 78.72 Quite High
Stomach Cancer 4 74.08 Quite High
Transitional Cell Carcinoma 16 69.12 Quite High
Renal Cancer 20 55.56 Quite High
Chromosome Aberrations 4 55.48 Quite High
Thyroid Neoplasm 4 47.60 Quite Low
Renal Cell Carcinoma 52 46.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, lack of Fez1 protein correlated with a poorer prognosis in 90% of patients with median survival of 17 months.
Negative_regulation (lack) of Fez1
1) Confidence 0.39 Published 2004 Journal BMC Urol Section Body Doc Link PMC517938 Disease Relevance 1.23 Pain Relevance 0
Statistical analysis showed a statistical trend (P = 0.06) between loss and reduction of Fez1 and presence of lymph node metastases.


Negative_regulation (reduction) of Fez1 in lymph node associated with metastasis
2) Confidence 0.39 Published 2004 Journal BMC Urol Section Abstract Doc Link PMC517938 Disease Relevance 0.50 Pain Relevance 0
Loss and reduction of Fez1 were correlated with a higher prevalence of lymph node metastases (71% vs. 0%, p = 0.061), although the same was not true for distant metastases or tumor stage.
Negative_regulation (reduction) of Fez1 in lymph node associated with cancer and metastasis
3) Confidence 0.34 Published 2004 Journal BMC Urol Section Body Doc Link PMC517938 Disease Relevance 0.89 Pain Relevance 0.03
Loss and reduction of Fez1 were correlated with a higher prevalence of lymph node metastases (71% vs. 0%, p = 0.061), although the same was not true for distant metastases or tumor stage.
Negative_regulation (Loss) of Fez1 in lymph node associated with cancer and metastasis
4) Confidence 0.34 Published 2004 Journal BMC Urol Section Body Doc Link PMC517938 Disease Relevance 0.90 Pain Relevance 0.03

General Comments

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