INT17996

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Context Info
Confidence 0.37
First Reported 1991
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 40
Total Number 41
Disease Relevance 31.40
Pain Relevance 7.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp) extracellular region (Crp)
Anatomy Link Frequency
erythrocyte 5
white blood cell 4
platelet 2
joint 2
coronary artery 2
Crp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 250 100.00 Very High Very High Very High
Inflammatory marker 207 100.00 Very High Very High Very High
Pain 24 100.00 Very High Very High Very High
headache 12 100.00 Very High Very High Very High
Angina 97 99.76 Very High Very High Very High
Inflammatory response 50 98.80 Very High Very High Very High
rheumatoid arthritis 31 97.16 Very High Very High Very High
abdominal pain 6 96.96 Very High Very High Very High
methotrexate 1 94.64 High High
imagery 2 94.32 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 503 100.00 Very High Very High Very High
Cardiovascular Disease 94 100.00 Very High Very High Very High
Pressure And Volume Under Development 61 100.00 Very High Very High Very High
Pain 24 100.00 Very High Very High Very High
Headache 7 100.00 Very High Very High Very High
Injury 28 99.92 Very High Very High Very High
Arthritis 5 99.84 Very High Very High Very High
Insulin Resistance 63 99.80 Very High Very High Very High
Nicotine Addiction 725 99.76 Very High Very High Very High
Cv General 3 Under Development 120 99.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This report describes a 69-year-old woman who presented with acute monocular visual loss, ipsilateral headache, and elevated sedimentation rate and C-reactive protein.
C-reactive protein Binding (presented) of associated with headache
1) Confidence 0.37 Published 2006 Journal J Clin Rheumatol Section Abstract Doc Link 16484877 Disease Relevance 0.50 Pain Relevance 0.14
Association between C-reactive protein levels and subsequent cardiac events among patients with stable angina treated with coronary artery stenting.
C-reactive protein Binding (Association) of in coronary artery associated with angina
2) Confidence 0.37 Published 2003 Journal Am. J. Med. Section Title Doc Link 12829197 Disease Relevance 0.10 Pain Relevance 0.19
A moderate-to-strong association of the ACR criteria with pain (r = 0.54), the tender (r = 0.54) and swollen joint count (r = 0.31), grip strength (r = -0.49), C-reactive protein (r = 0.35), the HAQ disability index (r = 0.76), self-perceived global health (r = 0.58), and the Larsen radiological score (r = 0.32) was found.
C-reactive protein Binding (association) of in joint associated with pain
3) Confidence 0.36 Published 1995 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 7554563 Disease Relevance 0.63 Pain Relevance 0.35
Before operation, 1 h after the beginning, 1 h, 6 h, 12 h and 24 h after the operation following parameters were analyzed: interleukine-6, C-reactive protein and leukocyte count.
C-reactive protein Binding (count) of in leukocyte
4) Confidence 0.32 Published 2009 Journal Coll Antropol Section Abstract Doc Link 19662781 Disease Relevance 0.72 Pain Relevance 1.06
Prioritisation strategies based on the prognostic information conferred by C reactive protein, which is not currently measured in this context, or a combination of C reactive protein and estimated glomerular filtration rate, is unlikely to be cost effective.
reactive protein Binding (combination) of
5) Confidence 0.25 Published 2010 Journal BMJ : British Medical Journal Section Abstract Doc Link PMC2808469 Disease Relevance 0 Pain Relevance 0
Figure 2 shows that adding the novel circulating biomarker highly sensitive C reactive protein to the routinely measured estimated glomerular filtration rate has little scope for improved effectiveness (changing the day of coronary artery bypass grafting) with 90 day maximum waits, and none for shorter maximum waiting times.


reactive protein Binding (adding) of in coronary artery
6) Confidence 0.25 Published 2010 Journal BMJ : British Medical Journal Section Body Doc Link PMC2808469 Disease Relevance 0 Pain Relevance 0
Neither fibrinogen or C-reactive protein concentrations were significantly associated with angina pectoris when entered in the model simultaneously.
C-reactive protein Binding (associated) of associated with angina
7) Confidence 0.25 Published 2000 Journal J Clin Epidemiol Section Abstract Doc Link 10693909 Disease Relevance 1.08 Pain Relevance 0.48
These cross-sectional data showed a significant positive association between C-reactive protein concentration and myocardial infarction but not self-reported angina pectoris in the U.S. population.
C-reactive protein Neg (not) Binding (association) of associated with angina and myocardial infarction
8) Confidence 0.25 Published 2000 Journal J Clin Epidemiol Section Abstract Doc Link 10693909 Disease Relevance 1.03 Pain Relevance 0.40
This was not observed in those patients who received amlodipine monotherapy, in whom there was no systematic change in high-sensitivity C-reactive protein associated with ischaemia reduction [median 0.2 mg/L, P = 0.113 (Pearson's correlation coefficient ?
C-reactive protein Binding (associated) of associated with cv unclassified under development
9) Confidence 0.23 Published 2010 Journal European Heart Journal Section Body Doc Link PMC2966969 Disease Relevance 0.40 Pain Relevance 0
This is both consistent with prior research and not surprising since the strongest association between C-reactive protein and lipid measures is for triglycerides.
C-reactive protein Binding (association) of
10) Confidence 0.23 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 0.96 Pain Relevance 0.20
The direct associations of C-reactive protein with mortality decrement seen in these other studies—and the dose–response seen in our own study—suggest the latter.
C-reactive protein Binding (associations) of
11) Confidence 0.23 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.16 Pain Relevance 0.12
C-reactive protein, white blood cell count, and fibrinogen were all positively associated with increased smoking intensity (p ?
C-reactive protein Binding (associated) of in white blood cell associated with nicotine addiction
12) Confidence 0.23 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.54 Pain Relevance 0.19
C-reactive protein may be directly involved as it binds to degraded LDL particles, is deposited at the intima-media interface, co-localizes with complement, and attracts monocytes to atherosclerotic lesions (21).
C-reactive protein Binding (binds) of in monocytes associated with atherosclerosis
13) Confidence 0.23 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779284 Disease Relevance 1.22 Pain Relevance 0.09
C-reactive protein may predict the risk of cardiovascular disease, but its association with angina pectoris in the general population has not been clearly established, however.
C-reactive protein Binding (association) of associated with angina and cardiovascular disease
14) Confidence 0.22 Published 2000 Journal J Clin Epidemiol Section Abstract Doc Link 10693909 Disease Relevance 0.56 Pain Relevance 0.25
Bivariate analyses of smoking status showed that among the inflammatory risk factors, unadjusted C-reactive protein, white blood cell count, and fibrinogen were all significantly and positively associated with smoking status (p < 0.01).
C-reactive protein Binding (associated) of in white blood cell associated with nicotine addiction and inflammation
15) Confidence 0.21 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.72 Pain Relevance 0.11
This subsequent evaluation includes the use of such laboratory tests as complete blood cell count with differential count, Chem 20 health profile, erythrocyte sedimentation rate, and an arthritic panel (assessment of rheumatoid factor, antinuclear antibody, C-reactive protein).
C-reactive protein Binding (assessment) of in erythrocyte associated with arthritis
16) Confidence 0.20 Published 1997 Journal J Am Osteopath Assoc Section Abstract Doc Link 9029877 Disease Relevance 0.84 Pain Relevance 0.64
CASE: NA young Palestinian woman presented with recurrent episodes of pelvic pain with rebound tenderness, fever, and elevated white blood cell count, erythrocyte sedimentation rate, and C-reactive protein.
C-reactive protein Binding (presented) of in erythrocyte
17) Confidence 0.20 Published 2003 Journal Obstet Gynecol Section Body Doc Link 12738114 Disease Relevance 0.38 Pain Relevance 0
However, hip bone loss was found to be associated with raised baseline C-reactive protein levels, baseline MRI bone marrow oedema of the SIJs and the presence of radiographic sacroiliitis after 8 years.
C-reactive protein Binding (associated) of in SIJs
18) Confidence 0.20 Published 2010 Journal Ann. Rheum. Dis. Section Body Doc Link 20448291 Disease Relevance 0.08 Pain Relevance 0
C-reactive protein, white blood cell count, and fibrinogen were all positively associated with increased smoking intensity (p ?
C-reactive protein Binding (associated) of in white blood cell associated with nicotine addiction
19) Confidence 0.18 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.54 Pain Relevance 0.19
C-reactive protein is a pentaxin, highly conserved across species [17,20,21] and stimulated synergistically by both IL-6 and IL-1?
C-reactive protein Binding (pentaxin) of
20) Confidence 0.18 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.21 Pain Relevance 0.12

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