INT180300

From wiki-pain
Revision as of 17:32, 23 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.07
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (S100B) extracellular region (S100B) nucleus (S100B)
cytoplasm (S100B)
Anatomy Link Frequency
fat 2
astrocytes 2
S100B (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 45 100.00 Very High Very High Very High
bDMF 5 100.00 Very High Very High Very High
iatrogenic 4 90.84 High High
Inflammatory response 2 79.56 Quite High
depression 14 61.20 Quite High
anesthesia 3 51.40 Quite High
Central nervous system 4 5.00 Very Low Very Low Very Low
sSRI 4 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 51 98.64 Very High Very High Very High
Disease 10 97.36 Very High Very High Very High
Depression 56 93.60 High High
Neurodegenerative Disease 5 88.52 High High
Hypertension 2 82.92 Quite High
INFLAMMATION 2 79.20 Quite High
Stress 2 78.52 Quite High
Brain Injury 15 74.52 Quite High
Death 4 64.80 Quite High
Cognitive Disorder 7 58.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our study showed that an increase in fat mass might not in isolation be a major contributor to elevated S100B levels.
Positive_regulation (contributor) of Positive_regulation (elevated) of S100B in fat
1) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2937027 Disease Relevance 1.19 Pain Relevance 0.04
Our attempt to control the increased levels of S100B caused by contamination from the surgical field did not yield different results.
Positive_regulation (caused) of Positive_regulation (increased) of S100B
2) Confidence 0.47 Published 2004 Journal BMC Neurol Section Abstract Doc Link PMC544890 Disease Relevance 0.11 Pain Relevance 0
Antidepressants stimulate the secretion of neurotrophic factors, such as brain derived neurotrophic factor (BDNF).38 Antidepressants also enhance the secretion of S100B by astrocytes via serotonergic systems.15,39-41 Interestingly, in this study, the increase in serum S100B levels in response to treatment with antidepressants was more prominent in nonresponders than in responders.
Positive_regulation (stimulate) of Positive_regulation (increase) of S100B in astrocytes associated with antidepressant and bdmf
3) Confidence 0.41 Published 2008 Journal Psychiatry Investigation Section Body Doc Link PMC2796025 Disease Relevance 0.64 Pain Relevance 0.62
In Figure 3, note that BBBD caused an increase of S100B dimer but not of the S100A1-B heterodimer.
Neg (not) Positive_regulation (caused) of Positive_regulation (increase) of S100B dimer
4) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2937027 Disease Relevance 0.13 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox