INT181269

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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.43
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

vesicle-mediated transport (USE1) endoplasmic reticulum (USE1) lysosome (USE1)
USE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 50 100.00 Very High Very High Very High
psoriasis 7 98.92 Very High Very High Very High
cINOD 4 98.68 Very High Very High Very High
Arthritis 26 96.36 Very High Very High Very High
Adalimumab 129 92.64 High High
Infliximab 6 66.80 Quite High
Etanercept 7 65.32 Quite High
antagonist 23 64.84 Quite High
rheumatoid arthritis 57 61.72 Quite High
Inflammation 13 53.52 Quite High
Disease Link Frequency Relevance Heat
Cramps 1 99.16 Very High Very High Very High
Psoriasis 8 98.92 Very High Very High Very High
INFLAMMATION 14 98.20 Very High Very High Very High
Seronegative Spondarthritis 21 96.36 Very High Very High Very High
Knee Injuries 1 91.44 High High
Disease 30 85.00 Quite High
Rheumatoid Arthritis 58 61.72 Quite High
Arthritis 8 59.92 Quite High
Disease Progression 4 43.60 Quite Low
Fatigue 2 18.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, surgeons performing ACL reconstruction use screws, pins, buttons, and cramps for graft fixation because of individual preference, or institutional orders.
Positive_regulation (performing) of Gene_expression (screws) of use associated with cramps
1) Confidence 0.24 Published 2005 Journal BMC Surg Section Body Doc Link PMC552311 Disease Relevance 0.19 Pain Relevance 0
Patients (n=313) were stratified according to MTX use (yes or no) and extent of psoriasis involvement (?
Positive_regulation (according) of Gene_expression (stratified) of use associated with psoriasis and methotrexate
2) Confidence 0.06 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936294 Disease Relevance 1.24 Pain Relevance 1.18
Mutation of the USEs in duplicate (USE 1,2 mut; USE 2,3 mut; USE 1,3 mut) resulted in approximately the same level of reduced polyadenylation efficiency as the USE 3 mut alone (Figure 4C).
Positive_regulation (resulted) of Gene_expression (alone) of USE 3
3) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0

General Comments

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