INT181409
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The supernatants from stromal cells accumulated IL-6, CXCL1, CCL20, and PGE in a concentration dependent manner for each LPS examined (Fig. 5AD; ANOVA, P<0.05). | |||||||||||||||
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The supernatants from epithelial cells also accumulated IL-6, CXCL1, and CCL20, in a concentration dependent manner for each LPS examined (Fig. 5EG; ANOVA, P<0.05), although the epithelial cells secreted little PGE (Fig. 5H). | |||||||||||||||
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In parallel, significant increases in CCR6 and CCL20, genes involved in the recruitment of Th17 cells, were only observed in colonic samples, supporting a less pronounced infiltration of Th17 cells in ileal inflammation. | |||||||||||||||
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Subsequent experiments used ultrapure LPS from E. coli and focused on the accumulation of IL-6, CXCL1, CCL20, and PGE. | |||||||||||||||
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Supernatants of the stromal cells treated with LPS accumulated IL-6, CXCL1, CCL20 and PGE over time (ANOVA, P<0.001) and in a treatment dependent manner (ANOVA, P<0.001) for each inflammatory mediator. | |||||||||||||||
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Epithelial cell supernatants also accumulated more IL-6, CXCL1 and CCL20 in response to LPS over time (ANOVA, P<0.001) and in a treatment dependent manner (ANOVA, P<0.001) for each mediator. | |||||||||||||||
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In all stages of EAE, CCL20 and CCR6 were upregulated in the CNS. | |||||||||||||||
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According to the calculated RTPC for the women in this study, the expected EST after EA is unaffected by acupuncture stimulation in the ST36 and ST38 except for four of the women. | |||||||||||||||
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