INT181576

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Context Info
Confidence 0.59
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 1.35
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos3) aging (Nos3) Golgi apparatus (Nos3)
cytoplasm (Nos3) signal transduction (Nos3) oxidoreductase activity (Nos3)
Anatomy Link Frequency
kidney cortex 2
kidney medulla 2
thoracic aorta 2
Nos3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 114 96.72 Very High Very High Very High
anesthesia 13 60.96 Quite High
ischemia 5 37.36 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Intracerebroventricular 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 14 90.76 High High
Diabetes Mellitus 792 77.12 Quite High
Cv General 4 Under Development 2 38.08 Quite Low
Coagulation Disorder 6 35.32 Quite Low
Brain Hemorrhage 2 19.16 Low Low
Hyperglycemia 42 6.84 Low Low
Renal Disease 48 5.00 Very Low Very Low Very Low
Body Weight 42 5.00 Very Low Very Low Very Low
Hypertrophy 30 5.00 Very Low Very Low Very Low
Body Weight Changes 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PreproET-1, iNOS, eNOS, total and phosphorylated p38-MAPK and ERK protein expressions of thoracic aorta, kidney cortex and kidney medulla were determined using standard SDS-PAGE and immunoblot technique.
Phosphorylation (phosphorylated) of eNOS in kidney medulla associated with medulla
1) Confidence 0.59 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0 Pain Relevance 0.09
The concentration of ET-1, NOx, creatinine and protein expression of preproET-1, iNOS, eNOS, phosphorylated p38-MAPK (pp38-MAPK), total p38-MAPK, phosphorylated ERK, total ERK were determined in the thoracic aorta, kidney cortex and kidney medulla obtained from each animal.


Phosphorylation (phosphorylated) of eNOS in kidney cortex associated with medulla
2) Confidence 0.45 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0.39 Pain Relevance 0.11
In addition, active Akt can phosphorylate endothelial nitric oxide synthase (eNOS), the activity of which increases NO production and the BBB permeability [43].
Phosphorylation (phosphorylate) of eNOS
3) Confidence 0.37 Published 2010 Journal BMC Neurol Section Body Doc Link PMC3020671 Disease Relevance 0.18 Pain Relevance 0
PreproET-1, iNOS, eNOS, total and phosphorylated p38-MAPK and ERK protein expressions of thoracic aorta, kidney cortex and kidney medulla were determined using standard SDS-PAGE and immunoblot technique.
Phosphorylation (phosphorylated) of eNOS in kidney cortex associated with medulla
4) Confidence 0.20 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0 Pain Relevance 0.09
PreproET-1, iNOS, eNOS, total and phosphorylated p38-MAPK and ERK protein expressions of thoracic aorta, kidney cortex and kidney medulla were determined using standard SDS-PAGE and immunoblot technique.
Phosphorylation (phosphorylated) of eNOS in thoracic aorta associated with medulla
5) Confidence 0.20 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0 Pain Relevance 0.09
The concentration of ET-1, NOx, creatinine and protein expression of preproET-1, iNOS, eNOS, phosphorylated p38-MAPK (pp38-MAPK), total p38-MAPK, phosphorylated ERK, total ERK were determined in the thoracic aorta, kidney cortex and kidney medulla obtained from each animal.


Phosphorylation (phosphorylated) of eNOS in thoracic aorta associated with medulla
6) Confidence 0.15 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0.39 Pain Relevance 0.11
The concentration of ET-1, NOx, creatinine and protein expression of preproET-1, iNOS, eNOS, phosphorylated p38-MAPK (pp38-MAPK), total p38-MAPK, phosphorylated ERK, total ERK were determined in the thoracic aorta, kidney cortex and kidney medulla obtained from each animal.


Phosphorylation (phosphorylated) of eNOS in kidney medulla associated with medulla
7) Confidence 0.15 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0.39 Pain Relevance 0.11

General Comments

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