INT182409

Context Info Confidence 0.36 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.33 Pain Relevance 0

nucleoplasm (OGG1) mitochondrion (OGG1) lyase activity (OGG1) hydrolase activity, acting on glycosyl bonds (OGG1) nucleolus (OGG1) nucleus (OGG1)

OGG1 (Homo sapiens)

Pain Link Frequency Relevance Heat Glutamate 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Stress 1 95.36 Cancer 9 94.20 Cockayne Syndrome 2 5.00 Pain 1 5.00 Disease 1 5.00 Aging 1 5.00 Adenoma 1 5.00 Contagious Ecthyma 1 5.00 Colon Cancer 1 5.00 Carcinoma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant Numerous lines of evidence support the role of oxidative stress in different types of cancer.

Negative_regulation (disrupted) of Localization (relocalization) of hOGG1 associated with stress and cancer

1) Confidence 0.36 Published 2005 Journal Nucleic Acids Research Section Title Doc Link PMC1072800 Disease Relevance 0.33 Pain Relevance 0

General Comments

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