INT182417

Context Info Confidence 0.44 First Reported 2005 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.83 Pain Relevance 0

nucleoplasm (OGG1) mitochondrion (OGG1) lyase activity (OGG1) hydrolase activity, acting on glycosyl bonds (OGG1) nucleolus (OGG1) nucleus (OGG1)

Anatomy Link Frequency nucleus 1 OGG1 (Homo sapiens)

Pain Link Frequency Relevance Heat cerebral cortex 1 5.00 transdermal 1 5.00 adenocard 1 5.00 Angina 1 5.00 Glutamate 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Cancer 29 96.88 Angiomyolipoma 12 92.00 Myeloid Leukemia 5 83.92 Renal Disease 1 73.08 Disease 22 60.84 Tuberous Sclerosis 11 50.00 Cyst 4 44.36 Lymphangioleiomyomatosis 11 5.00 Convulsion 9 5.00 Hamartoma 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

At this time, EGFP-hOGG1 is mainly distributed evenly throughout the nucleus (Figure 4).

Positive_regulation (distributed) of EGFP-hOGG1 in nucleus

1) Confidence 0.44 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1072800 Disease Relevance 0 Pain Relevance 0

Genetic variations in OGG1 gene have been shown to modulate DNA repair capacity and are related risk of tumour development.

Positive_regulation (variations) of OGG1 associated with cancer

2) Confidence 0.25 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.83 Pain Relevance 0

General Comments

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