INT182560

Context Info Confidence 0.12 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.31 Pain Relevance 1.02

signal transduction (Ptger2, Ptgir) plasma membrane (Ptger2, Ptgir) signal transducer activity (Ptger2, Ptgir)

Ptger2 (Mus musculus) Ptgir (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 2 93.12 dorsal root ganglion 27 92.64 Analgesic 1 90.84 Inflammation 18 86.88 Pain 7 70.84 nociceptor 1 62.68 substance P 1 61.04 cytokine 1 59.64 bradykinin 3 58.32 qutenza 50 47.44

Disease Link Frequency Relevance Heat INFLAMMATION 23 92.56 Ganglion Cysts 27 91.68 Injury 2 86.20 Nociception 11 81.80 Pain 8 70.84 Hyperalgesia 18 5.00 Inflammatory Pain 4 5.00 Sprains And Strains 3 5.00 Hypersensitivity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Prostaglandins act upon a family of pharmacologically distinct prostanoid receptors including EP1, EP2, EP3, EP4 and IP that activate several different G protein-coupled signaling pathways [2,4,5].

EP2 Positive_regulation (activate) of IP

1) Confidence 0.12 Published 2005 Journal Mol Pain Section Body Doc Link PMC1074353 Disease Relevance 1.31 Pain Relevance 1.02

General Comments

This test has worked.